胡亦辰-天津大学医学院

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胡亦辰

职称/职务:英才副教授

办公室:医工院办公楼213

邮箱:yhu@tju.edu.cn

个人简介：

胡亦辰博士长期从事磁共振技术的研究，于2017年毕业于美国伊利诺伊大学，获磁共振专业博士学位，后入职United Imaging Healthcare, America (联影医疗美国)磁共振研究中心任Senior Scientist，后任Lead Scientist，任职期间主持了多项磁共振高级应用的技术开发和研究，成功应用于三甲医院的临床诊断和高校及科研院所的研究之中，并产生了多篇学术论文及十余项专利。在神经影像序列方面，主持了3D ASL，多PLD ASL等技术研发，以非侵入式的标记获得脑血流灌注的定量信息，助力脑神经科研；实现了拥有业界自主知识产权的多对比度成像技术-Multiplex的基础序列，已体现出突出的科研价值。此外，主持了多种快速成像采集序列的研发，包括3D GRASE和3D FSE Spiral等用以作为磁共振高级应用的采集方法，并在3D GRE Spiral和3D bSSFP Spiral序列的研发过程中形成了SPARTA-3D序列簇集，可用于全身各部位的高时空分辨率的动态3D实时磁共振采集，对于手术介入以及放射治疗的3D磁共振导航场景具有实用的临床应用价值，此外SPARTA-3D在多种心脏磁共振序列扫描中也具有临床推广前景。

主要研究方向：

● 磁共振动脉自旋标记技术(ASL)，脑血流灌注动力学

● 磁共振快速成像序列

● 实时磁共振成像方法

● 磁共振成像方法在手术介入与治疗的临床应用

代表性学术成果：

论文：

	▪ Li, H., Liu, Q., Dong, X., Guo, Z., Wang, K., Liu, S., Liu, Q., Ye, Y., Hu, Y., Zhong, Z., Liu, H., Zhu, Y., Wang, H., Liang, D., Xu, J., and Zhou, Y., “Robust cardiac T1 mapping in three heartbeats with UltraMAP: a synergistic CNN-FC approach”. IEEE International Symposium on Biomedical Imaging (ISBI).		May 2024
	▪ Hu, Y., Zhong, Z., Liu, Q., Li, H., Liu, H., Ye, Y., and Xu, J., “Feasibility of real-time 3D whole heart MR cine based on bssfp sequence using spiral in-out trajectory”. Journal of Cardiovascular Magnetic Resonance. (IF=4.2)		Mar 2024
	▪ Hu, J., Guo, M., Hu, Y., Liu, Q., Ye, Y., and Xu, J., “A dual interleaved k-space trajectory for robust bssfp imaging of high-quality cardiac cine MRI”. Journal of Cardiovascular Magnetic Resonance. (IF=4.2)		Mar 2024
	▪ Hu, Y., Wei, Q., Zhou, Z., Hu, J., Xie, J. and Xu, J., “Customized whole brain-covering 3D GRASE in multi-delay pseudo-continuous arterial spin labeling for duplex distinct hemodynamic mapping contrasts of brain tissues and circulation pathways”. Physics in Medicine and Biology. (IF=4.174)		Aug 2022
	▪ Ye, Y., Lyu, J., Hu, Y., Zhang, Z., Xu, J., Zhang, W., Yuan, J., Zhou, C., Fan, W., and Zhang, X., “Augmented T1-weighted steady state magnetic resonance imaging”. NMR in Biomedicine. (IF=4.044)		Mar 2022
	▪ Ye, Y., Lyu, J., Hu, Y., Zhang, Z., Xu, J., and Zhang, W., “MULTI-parametric MR imaging with fLEXible design (MULTIPLEX)”. Magnetic Resonance in Medicine. (IF=4.668)		Aug 2021
	▪ Chen, E.Z., Ye, Y., Chen, X., Lyu, J., Zhang, Z., Hu, Y., Chen, T., Xu, J., and Sun, S., “Accelerating 3D MULTIPLEX MRI Reconstruction with Deep Learning”. Cornell University, arXiv.org > eess > arXiv:2105.08163.		May 2021
	▪ Nacken, T.J., Halbig, C.E., Wawra, S.E., Damm, C., Romeis, S., Walter, J., Tehrani, M.J., Hu, Y., Ishii, Y., Eigler, S., and Peukert, W., “Structural factors controlling size reduction of graphene oxide in liquid processing”. Carbon. (IF=9.594)		Dec 2017
	▪ Hu, Y., Shim, Y., Oh, J., Park, Sunghee, Park, Sungjin, and Ishii, Y., “Synthesis of ¹³C, ¹⁵N-labeled graphitic carbon nitrides and NMR-based evidence of hydrogen-bonding assisted two-dimensional assembly”. Chemistry of Materials. (IF= 9.811)		May 2017
	▪ Wang, Z., Eigler, S., Ishii, Y., Hu, Y., Papp, C., Lytken, O., Steinrück, H.P., and Halik, M., “A facile approach to synthesize an oxo-functionalized graphene/polymer composite for low-voltage operating memory devices”. Journal of Materials Chemistry C, 3(33), pp.8595-8604. (IF=7.393)		Jul 2015
	▪ Eigler, S., Hu, Y., Ishii, Y., and Hirsch, A., “Controlled functionalization of graphene oxide with sodium azide”. Nanoscale, 5(24), pp.12136-12139. (IF= 7.790)		Oct 2013
	▪ Park, S., Hu, Y., Hwang, J.O., Lee, E.S., Casabianca, L.B., Cai, W., Potts, J.R., Ha, H.W., Chen, S., Oh, J., Kim, S.O., Kim, Y.H., Ishii, Y. and Ruoff, R.S., “Chemical structures of hydrazine-treated graphene oxide and generation of aromatic nitrogen doping”. Nature Communications, 3, p.638. (IF= 14.919)		Jan 2012
会议: ▪ Hu, Y., Hu, J., Zhong, Z., Padua, A., Liu, Q., Ye, Y., and Xu, J., “SPARTA-3D: 3D real-time tracking solution for interventional MRI”, International Society for Magnetic Resonance in Medicine Annual Meeting & Exhibition, 2024. Oral Power Pitch.		May 2024
▪ Hu, Y., Zhong, Z., Hu, J., Li, H., Liu, H., Liu, Q., Ye, Y., and Xu, J., “3D real-time whole heart cine MR based on spiral-in/out bssfp sequence”, International Society for Magnetic Resonance in Medicine Annual Meeting & Exhibition, 2024. Digital Poster.		May 2024
▪ Hu, Y., Hu, J., Zhang, Z., Liu, H., Liu, Q., Ye, Y., and Xu, J., “Subject-specific circular artifacts in ASL perfusion imaging with 3D stack-of-spirals FSE readout”, International Society for Magnetic Resonance in Medicine Annual Meeting & Exhibition, 2023. Digital Poster.		Jun 2023
▪ Hu, Y., Wei, Q., Zhou, Z., Hu, J., Xie, J. and Xu, J., “Customized whole-brain covering GRASE in multi-delay pCASL for distinct contrasts and adequate SNRs in hemodynamic parameter mappings”, International Society for Magnetic Resonance in Medicine 30th Annual Meeting & Exhibition, 2022 . Oral Power Pitch.		Dec 2021
▪ Hu, Y., and Hu, J., “Simplified Phase-Sensitive Inversion Recovery (PSIR) Reconstruction using Multi-dimensional Integration (MDI) for Elevated SNR”, International Society for Magnetic Resonance in Medicine 29th Annual Meeting & Exhibition, 2021. Digital Poster.		Feb 2021
▪ Chen, E.Z., Ye, Y., Chen, X., Lyu, J., Zhang, Z., Hu, Y., Chen, T., Xu, J., and Sun, S., “Accelerating 3D MULTIPLEX MRI Reconstruction with Deep Learning”, International Society for Magnetic Resonance in Medicine 29th Annual Meeting & Exhibition, 2021. Digital Poster.		Feb 2021
▪ Ye, Y., Lyu, J., Hu, Y., Zhang, Z., Xu, J., and Zhang, W., “MULTI-Parametric MR imaging with fLEXible modular design (MULTIPLEX)”, International Society for Magnetic Resonance in Medicine 29th Annual Meeting & Exhibition, 2021. Oral Talk.		Feb 2021
▪ Ye, Y., Lyu, J., Hu, Y., Zhang, Z., Xu, J., and Zhang, W., “Augmented T1 weighted (aT1W) contrast imaging”, International Society for Magnetic Resonance in Medicine 29th Annual Meeting & Exhibition, 2021. Digital Poster.		Feb 2021
▪ Hu, Y., Wei, Q., Zhou, Z., Xie, J. and Ye, Y., “Noise reduction and ghosting alleviation in ASL perfusion measurement using multi-dimensional integration (MDI)”, International Society for Magnetic Resonance in Medicine 28th Annual Meeting & Exhibition, 2020. Digital Poster.		Feb 2020
▪ Li, G., Liu, H., Liu, Q., Ye, Y., Hu, Y., Qin, H., Xie, J., Yan, J., Xin, Y. and Jiang, G., “A comparative analysis of CEST-APT, SWI-QSM, DWI and ASL-CBF in ischemic stroke patients”, International Society for Magnetic Resonance in Medicine 28th Annual Meeting & Exhibition, 2020. Oral Talk.		Feb 2020
▪ Ye, Y., Lv, J., Hu, Y., Zhang, Z., Xu, J. and Zhang W., “Complex semi-quantitative noise analysis for single set of MR images”, International Society for Magnetic Resonance in Medicine 28th Annual Meeting & Exhibition, 2020. Digital Poster.		Feb 2020
▪ Hu, Y., Eigler, S., Ruoff. R.S. and Ishii, Y., “Characterizations of chemically modified graphite/graphene oxide by NMR and ab-initio calculations”, International Society of Magnetic Resonance (ISMAR) 2015. Poster Presentation.		Aug 2015
▪ Hu, Y., Eigler, S., Ruoff. R.S. and Ishii, Y., “Solid-state NMR investigation of chemically modified graphite/graphene-based materials”, Chicago Area NMR Meeting for Midwest-2014. Northwestern University, Evanston, IL. Invited Talk.		Nov 2014
▪ Hu, Y., Wang, S., Zhu, Y., Ruoff, R.S. and Ishii, Y., “Structural analysis of activated microwave-expanded graphite oxide and its confining behavior for small molecules by solid-state NMR and solution NMR”, 54^th Experimental NMR Conference-2013. Poster Presentation.		Apr 2013
▪ Wang, S., Hu, Y., Park, S., Ruoff, R.S. and Ishii, Y., “Characterization of chemical reactions and structures for hydrazine-treated graphene oxide and porous graphene-based materials by solid-state NMR and ab-initio calculations”, 54^th Rocky Mountain Conference on Magnetic Resonance-2012. Poster Presentation.		Jul 2012
▪ Hu, Y., Park, S., Ruoff, R.S. and Ishii, Y., “Characterization of reduced graphite oxide by ¹³C and ¹⁵N solid-state NMR and ab-initio calculations”, 52^nd Experimental NMR Conference-2011. Poster Presentation.		Apr 2011

著作章节：

▪ 《磁共振成像技术与应用》上海科学技术出版社

2022

专利：

▪ Hu, Y., and Xu, J., “A 3D MR imaging method, system, and media”. Chinese Patent.	2024
▪ Hu, Y., and Hu, J., “A density-compensation determination method, system, and media”. Chinese Patent.	2023
▪ Hu, Y., and Hu, J., “An image reconstruction method, system, and media”. Chinese Patent.	2023
▪ Hu, Y., and Hu, J., “An echo-time shifting method in echo-planar imaging in MRI”. Chinese Patent.	2021
▪ Hu, Y., and Hu, J., “A perfusion and CBF quantification method in arterial spin labeling MRI”. Chinese Patent.	2021
▪ Hu, J., and Hu, Y., “An anatomical image acquisition method in MRI”. Chinese Patent.	2021
▪ Hu, J., and Hu, Y., “An automatic positioning method in MRI”. Chinese Patent.	2021
▪ Hu, J., and Hu, Y., “A self-navigated dynamic cardiovascular imaging method in MRI”. Chinese Patent.	2021
▪ Hu, J., and Hu, Y., “A quantification imaging interface in MRI”. Chinese Patent.	2021
▪ Hu, Y., and Hu, J., “A variable contrast spiral imaging acquisition method in MRI”. Chinese Patent. 202110720949.9	2020
▪ Hu, Y., and Hu, J., “A k-space data sampling and regridding method in MRI”. Chinese Patent. 202110721080.X	2020
▪ Wei, Q., Xie, J., and Hu, Y., “Artifact elimination method of ASL imaging based on GRASE readout”. Chinese Patent. 202010285038.3	2020
▪ Liu, H., Liu, Q., and Hu, Y., “Simultaneous acquisition of APT, pH weighted image, R2, R2, R2’ images and myelin water fraction map by using 2D/3D GRASE sequence”. Chinese Patent. 202111106476.X*	2019
▪ Liu, H., Liu, Q., and Hu, Y., “Systems and methods for magnetic resonance imaging”. US Patent. US17/033,001	2019