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范秋筠

职称/职务:教授
办公室:天津大学医工院2楼207室
邮箱:fanqiuyun@tju.edu.cn

个人简介

范秋筠,国家级青年人才,国家重点研发计划项目首席科学家,天津大学英才教授,博士生导师,天津大学医学院院长助理,民主建国会天津大学委员会副主委,曾任哈佛医学院讲师,分别于浙江大学、美国范德比尔特大学取得学士和博士学位。从事新型弥散磁共振成像技术及其在人类脑连接图谱、脑网络与认知功能、神经系统疾病早期诊断中的应用。入选“国家海外高层次人才计划”、国际医学磁共振学会青年会士,获海外华人医学磁共振学会青年学者、美国心脏和脑卒中学会博士后会士等荣誉称号。主持科技部国家重点研发项目、国家自然科学基金面上项目、省部级重点项目等。

 

主要研究方向

磁共振成像,医学影像数据处理,认知和疾病的脑影像关联,智能算法在医学影像及数据分析中的应用等。


代表性学术成果

1. Wichtmann, B.D.#, Fan, Q.#, Eskandarian, L., Witzel, T., Attenberger, U.I., Pieper, C.C., Schad, L., Rosen, B.R., Wald, L.L., Huang, S.Y., Nummenmaa, A., 2023. Linear multi-scale modeling of diffusion MRI data: A framework for characterization of oriented structures across length scales. Human Brain Mapping 44, 1496-1514.

2. Li, Z., Fan, Q., Bilgic, B., Wang, G., Wu, W., Polimeni, J.R., Miller, K.L., Huang, S.Y., Tian, Q., 2023. Diffusion MRI data analysis assisted by deep learning synthesized anatomical images (DeepAnat). Medical Image Analysis 86, 102744.

3. Fan, Q., Eichner, C., Afzali, M., Mueller, L., Tax, C.M.W., Davids, M., Mahmutovic, M., Keil, B., Bilgic, B., Setsompop, K., Lee, H.-H., Tian, Q., Maffei, C., Ramos-Llordén, G., Nummenmaa, A., Witzel, T., Yendiki, A., Song, Y.-Q., Huang, C.-C., Lin, C.-P., Weiskopf, N., Anwander, A., Jones, D.K., Rosen, B.R., Wald, L.L., Huang, S.Y., 2022. Mapping the Human Connectome using Diffusion MRI at 300 mT/m Gradient Strength: Methodological Advances and Scientific Impact. NeuroImage, 2022; 118958. (Invited Review)

4. Fan, Q.,  Polackal, M.N., Tian, Q., Ngamsombat, C., Nummenmaa, A., Witzel, T., Klawiter, E.C., Huang, S.Y. Scan-rescan repeatability of axonal imaging metrics using high-gradient diffusion MRI and statistical implications for study design. Neuroimage 2021;240:118323.

5. Fan, Q. , Nummenmaa, A., Witzel, T., Ohringer, N., Tian, Q., Setsompop, K., Klawiter, E.C., Rosen, B.R., Wald, L.L., Huang, S.Y. Axon diameter index estimation independent of fiber orientation distribution using high-gradient diffusion MRI. NeuroImage 2020;222:117197.

6. Fan, Q., Tian, Q., Ohringer, N.A., Nummenmaa, A., Witzel, T., Tobyne, S.M., Klawiter, E.C., Mekkaoui, C., Rosen, B.R., Wald, L.L., Salat, D.H., Huang, S.Y. Age-related alterations in axonal microstructure in the corpus callosum measured by high-gradient diffusion MRI. Neuroimage 2019;191:325-336.

7. Fan, Q., Nummenmaa, A., Wichtmann, B., Witzel, T., Mekkaoui, C., Schneider, W., Wald, L.L., Huang, S.Y. Validation of diffusion MRI estimates of compartment size and volume fraction in a biomimetic brain phantom using a human MRI scanner with 300mT/m maximum gradient strength. Neuroimage 2018;182:469-478.

8. Setsompop, K., Fan, Q., Stockmann, J., Bilgic, B., Huang, S., Cauley, S.F., Nummenmaa, A., Wang, F., Rathi, Y., Witzel, T., Wald, L.L. High-resolution in vivo diffusion imaging of the human brain with generalized slice dithered enhanced resolution: Simultaneous multislice (gSlider-SMS). Magn Reson Med 2018;79(1):141-151.

9. Fan, Q., Nummenmaa, A., Polimeni, J.R., Witzel, T., Huang, S.Y., Wedeen, V.J., Rosen, B.R., Wald, L.L. HIgh b-value and high Resolution Integrated Diffusion (HIBRID) imaging. NeuroImage 2017;150:162-176.

10. Granberg, T., Fan, Q., Treaba, C.A., Ouellette, R., Herranz, E., Mangeat, G., Louapre, C., Cohen-Adad, J., Klawiter, E.C., Sloane, J.A., Mainero, C. In vivo characterization of cortical and white matter neuroaxonal pathology in early multiple sclerosis. Brain 2017;140(11):2912-2926.

11. Fan, Q., Witzel, T., Nummenmaa, A., Van Dijk, K.R.A., Van Horn, J.D., Drews, M.K., Somerville, L.H., Sheridan, M.A., Santillana, R.M., Snyder, J., Hedden, T., Shaw, E.E., Hollinshead, M.O., Renvall, V., Zanzonico, R., Keil, B., Cauley, S., Polimeni, J.R., Tisdall, D., Buckner, R.L., Wedeen, V.J., Wald, L.L., Toga, A.W., Rosen, B.R. MGH-USC Human Connectome Project datasets with ultra-high b-value diffusion MRI. Neuroimage 2016;124(Pt B):1108-1114.

12. Fan, Q., Anderson, A.W., Davis, N., Cutting, L.E. Structural connectivity patterns associated with the putative visual word form area and children's reading ability. Brain Res 2014;1586:118-129.

13. Fan, Q., Nummenmaa, A., Witzel, T., Zanzonico, R., Keil, B., Cauley, S., Polimeni, J.R., Tisdall, D., Van Dijk, K.R., Buckner, R.L., Wedeen, V.J., Rosen, B.R., Wald, L.L. Investigating the capability to resolve complex white matter structures with high b-value diffusion magnetic resonance imaging on the MGH-USC Connectom scanner. Brain Connect 2014;4(9):718-726.

14. Fan, Q., Davis, N., Anderson, A.W., Cutting, L.E. Thalamo-cortical connectivity: what can diffusion tractography tell us about reading difficulties in children? Brain Connect 2014;4(6):428-439.


科研项目

结题项目:

1. 美国心脏与脑卒中协会(AHA)博士后基金项目,17POST33670452TractCaliber MRI for Characterizing Axonal Damage in Ischemic Stroke2017/07/01-2019/6/30,主持。

2. 美国麻省总医院ECOR基金项目,HIBRID MRI for Characterizing Focal Cortical Dysplasia in Epilepsy2016/01/01-2016/12/31,主持。

在研项目:

1. 科技部重点研发计划项目,2023.11-2026.106000万元,主持;

2. 国家自然科学基金面上项目,2021.1-2024.1256万元,主持。


获奖情况

2020年,国家级优秀青年人才

2020年,天津大学北洋学者英才计划

2018年,国际医学磁共振学会青年会士

2018年,国际华人医学磁共振学会青年学者一等奖

2017-19年,美国心脏及脑卒中学会Postdoc Fellowship

2016年,国际医学磁共振学会Magna Cum Laude Merit Award

2015年,国际医学磁共振学会Summa Cum Laude Merit Award


社会学术兼职

中国图象图形学会-脑图谱专家委员会,委员

The Innovation》青年编委

Military Medical Research》青年编委

国际医学磁共振学会程序委员会青年委员

北美放射协会(RSNA)定量影像学生物标记协会磁共振成像委员会委员

Frontiers in Neuroscience》期刊客座编辑

审稿人:NeuroImage, Magnetic Resonance in Medicine, Human Brain Mapping, IEEE Transactions on Medical Imaging, American Journal of Neuroradiology, Nature Scientific Reports, Magnetic Resonance Materials in Physics, Biology and Medicine, IEEE Journal of Biomedical and Health Informatics, Journal of Magnetic Resonance Imaging, Neurobiology of Aging, NeuroImage: Clinical