佟小光
个人简介
佟小光,神经外科博士,主任医师,博士生导师,现任天津市环湖医院党委副书记、院长,天津市神经外科研究所所长。已获批天津市有突出贡献专家、市131创新型一层次人才、市131创新团队带头人等称号;先后主持承担国家重点研发计划1项、天津市科委科技支撑2项、天津市卫生健康科技重点攻关1项;2019年以来以通讯/共同通讯作者,发表SCI文章32篇;获天津市科技进步二等奖1项(排名第2)。
主要研究方向
脑血流重建新术式研发;显微神经解剖
代表性学术成果
1.Liao J, Zhang M, Shi Z, Lu H, Wang L, Fan W, Tong X*, Yan H*. Improving the Function of Meningeal Lymphatic Vessels to Promote Brain Edema Absorption after Traumatic Brain Injury. Journal of neurotrauma. 2022.(共同通讯作者)
2.Wang B, Tian F, Tong X*. Clinical Grading System, Surgical Outcomes and Prognostic Analysis of Cranial Base Chordomas. Journal of Korean Neurosurgical Society. 2022;65:469-478.(通讯作者)
3.Zhao H, Tong X*. Bypass Surgery Management of Complex Proximal and Distal Posterior Inferior Cerebellar Artery Aneurysms. The Journal of craniofacial surgery. 2022;33:2049-2054. (通讯作者)
4.Song S, Wu H, Wang F, Jiao J, Xu L, Wang H, Tong X*, Yan H*. Global research trends and hotspots on glioma stem cells. Frontiers in oncology. 2022;12:926025. (共同通讯作者)
5.Bao J, Tong X*, Wu R, Yun Q. Analysis of Risk Factors for Vulnerable Plaque Formation and Pathogenic in Carotid Artery. The Journal of craniofacial surgery. 2022. (通讯作者)
6.Li Q, Wang B, Sun Y, Qiao J, Tong X*. Association between Cerebrovascular Risk Factors and Collateral Compensation in Chronic Symptomatic Intracranial Vertebrobasilar Stenosis. European neurology. 2022:1-8. (通讯作者)
7.Ding M, Wang X, Zhao H, Shi M, Shang Y, Wang H, Wang X, Tong X*. Internal Carotid Artery Constriction with or without Superficial Temporal Artery-Middle Cerebral Artery Bypass for Patients with Giant Internal Carotid Aneurysms. World neurosurgery. 2022;164:e662-e670. (通讯作者)
8.Cui Y, Xu L, Wang F, Wang Z, Tong X*, Yan H*. Orally Administered Brain Protein Combined With Probiotics Increases Treg Differentiation to Reduce Secondary Inflammatory Damage Following Craniocerebral Trauma. Frontiers in immunology. 2022;13:928343. (共同通讯作者)
9.Sun Y, Gao K, Shi M, Shang Y, Tong X*. Superficial Temporal Artery-Posterior Cerebral Artery Bypass Through Zygomatic Anterior Temporal Approach for Complex Posterior Cerebral Artery Aneurysm. World neurosurgery. 2022;159:110-119. (通讯作者)
10.Wang B, Li Q, Sun Y, Tong X*. Surgical Strategy for Skull Base Chordomas : Transnasal Midline Approach or Transcranial Lateral Approach. Journal of Korean Neurosurgical Society. 2022;65:457-468. (通讯作者)
11.Sun Y, Yang J, Li T, Gao K, Tong X*. Nomogram for Predicting Facial Nerve Outcomes After Surgical Resection of Vestibular Schwannoma. Frontiers in neurology. 2021;12:817071. (通讯作者)
12.Liang B, Zhou Y, Jiao J, Xu L, Yan Y, Wu Q, Tong X*, Yan H*. Integrated Analysis of Transcriptome Data Revealed AURKA and KIF20A as Critical Genes in Medulloblastoma Progression. Frontiers in oncology. 2022;12:875521. (共同通讯作者)
13.Zhou Y, Wu H, Wang F, Xu L, Yan Y, Tong X*, Yan H*. GPX7 Is Targeted by miR-29b and GPX7 Knockdown Enhances Ferroptosis Induced by Erastin in Glioma. Frontiers in oncology. 2021;11:802124. (共同通讯作者)
14.Zhao H, Tong X*, Wang X, Ding M , Zhang K. Ischemic stroke following STA-MCA double bypass. Translational neuroscience. 2022;13:20-29. (通讯作者)
15.Xu L, Wu Q, Yan H, Shu C, Fan W, Tong X*, Li Q*. Long noncoding RNA KB-1460A1.5 inhibits glioma tumorigenesis via miR-130a-3p/TSC1/mTOR/YY1 feedback loop. Cancer letters. 2022;525:33-45. (共同通讯作者)
16.Guo F, Li Z, Tian C, Yan Y, Yao X, Tong X*, Yan H*. Correlation Between Anatomic Variations of Sphenoid Sinuses and Pituitary Adenoma. The Journal of craniofacial surgery. 2021;32:1685-1688. (共同通讯作者)
17.Song S, Ma D, Xu L, Wang Q, Liu L, Tong X*, Yan H*. Low-intensity pulsed ultrasound-generated singlet oxygen induces telomere damage leading to glioma stem cell awakening from quiescence. iScience. 2022;25:103558. (共同通讯作者)
18.Wu H, Zhou Y, Wu H, Xu L, Yan Y, Tong X*, Yan H*. CENPN Acts as a Novel Biomarker that Correlates With the Malignant Phenotypes of Glioma Cells. Frontiers in genetics. 2021;12:732376. (共同通讯作者)
19.Sun Y, Zhang W, Wang B, Li Q, Shi M, Tong X*. Bypass Surgery to Treat Giant Cavernous Carotid Artery Aneurysms. The Journal of craniofacial surgery. 2021;32:e563-e567. (通讯作者)
20.Hou Y, Xu L, Song S, Fan W, Wu Q, Tong X*, Yan H*. Oral Administration of Brain Protein Combined With Probiotics Induces Immune Tolerance Through the Tryptophan Pathway. Frontiers in molecular neuroscience. 2021;14:634631. (共同通讯作者)
21.Zhou Y, Zhang L, Song S, Xu L, Yan Y, Wu H, Tong X*, Yan H*. Elevated GAS2L3 Expression Correlates With Poor Prognosis in Patients With Glioma: A Study Based on Bioinformatics and Immunohistochemical Analysis. Frontiers in genetics. 2021;12:649270. (共同通讯作者)
22.Wen H, Li Z, Song S, Xu L, Tong X*, Yan H*. Silencing of lncRNA LBX2-AS1 suppresses glioma cell proliferation and metastasis through the Akt/GSK3β pathway in vitro. Acta biochimica et biophysica Sinica. 2021;53:446-453. (共同通讯作者)
23.Du T, Jing X, Song S, Lu S, Xu L, Tong X*, Yan H*. Therapeutic Effect of Enteral Nutrition Supplemented with Probiotics in the Treatment of Severe Craniocerebral Injury: A Systematic Review and Meta-Analysis. World neurosurgery. 2020;139:e553-e571. (共同通讯作者)
24.Xu L, Li Z, Song S, Chen Q, Mo L, Wang C, Fan W, Yan Y, Tong X*, Yan H*. Downregulation of α-l-fucosidase 1 suppresses glioma progression by enhancing autophagy and inhibiting macrophage infiltration. Cancer science. 2020;111:2284-2296. (共同通讯作者)
25.Li H, Liang S, Yu Y, Wang Y, Cheng Y, Yang H, Tong X*. Effect of Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) on balance performance in Parkinson's disease. PloS one. 2020;15:e0238936. (通讯作者)
26.Sun Y, Wan B, Li Q, Li T, Huang G, Zhang W, Yang J, Tong X*. Endovascular Treatment for Cavernous Carotid Aneurysms: A Systematic Review and Meta-Analysis. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2020;29:104808. (通讯作者)
27.Wang X, Tong X*, Liu J, Shi M, Shang Y, Wang H. Tailored Communicating Bypass for the Management of Complex Anterior Communicating Artery Aneurysms: "Flow-Counteraction" In Situ Bypass and Interposition Bypass Using Contralateral A2 Orifice as Donor Site. Operative neurosurgery (Hagerstown, Md). 2020;19:117-125. (通讯作者)
28.Tong X* and Yang Y. Editorial. Lessons learned: special precautions for performing emergency cerebrovascular procedures amid the COVID-19 pandemic. Journal of neurosurgery. 2020:1-2. (通讯作者)
29.Li H, Liang S, Yu Y, Wang Y, Cheng Y, Yang H, Tong X*. Clinical experience of comprehensive treatment on the balance function of Parkinson's disease. Medicine. 2020;99:e20154. (通讯作者)
30.Wang H, Zhang Y, Zhang C, Tong X*. Screening prognosis-related genes in glioblastoma by microarray analysis. Anti-cancer drugs. 2020;31:150-157. (通讯作者)
31.Lu S, Du T, Sun Z, Xu L, Tong X*, Yan H*. Timing of Extremity Fracture Fixation in Patients with Traumatic Brain Injury: A Meta-Analysis of Prognosis. World neurosurgery. 2020;133:227-236. (共同通讯作者)
32.Wang X, Tong X*, Shi M, Shang Y, Wang H. Occipital Artery to Extradural Vertebral Artery Bypass for Posterior Circulation Ischemia. Operative neurosurgery (Hagerstown, Md). 2019;16:527-538. (通讯作者)
33. Wang F, Xu L, Wen B, Song S, Zhou Y, Wu H, Wu Q, Wang Y, Tong X, Yan H. Ultrasound-excited temozolomide sonosensitization induces necroptosis in glioblastoma. Cancer Lett. 2023 Feb 1;554:216033. (共同通讯作者)
科研项目
“人工酶电极的临床应用研究”,国家重点研发计划,编号2021YFF1200705,经费546.92万元,主持在研;
“椎基底系统血流重建手术的规范化研究”,科技重大专项与工程老年常见疾病防控技术研究重大专项,编号18ZXDBSY00180 100,经费100万元,主持在研;
“脑卒中的早期防治与临床诊治规范化研究”,天津市科技局科技支撑项目,编号13ZCZDSY01600,经费100万元,主持已结题。
获奖情况
2016年“脑卒中多学科联动防治模式及关键技术研发集成” 获得天津市科技进步二等奖,第2完成人,证书编号:2016JB-2-045-R2
社会学术兼职
天津市医学会神经外科分会副主任委员;中国医师协会神经外科分会全国委员;中国神经科学学会神经外科基础与临床分会委员;国家卫健委能力建设与继续教育神经外科学专家委员会神经外科基础学组组长;世界神经外科协会联盟会员;中华中青年神经外科交流协会副会长;北美颅底外科协会委员;《中国现代神经疾病杂志》副主编。