李洁，主任医师，教授，博士毕业于德国维尔茨堡大学，博士生导师，享受国务院政府特殊津贴，首届“天津名医”，现任天津市安定医院院长。中华医学会精神医学分会委员、中国心理卫生协会常务理事、美国哈佛大学麦可林精神科医院访问学者。从事精神医学临床、科研、教学工作二十余年，主持完成国家自然科学基金、天津市自然科学基金等科研项目；在国内外专业杂志上发表论文100余篇。

生物精神病学，临床精神病学

（1） Meijuan Li#, Ying Liu#, Yuying Qiu, Jing Zhang, Yonghui Zhang, Yongping Zhao, Qiong Jia, Jie Li*. The effect of berberine adjunctive treatment on glycolipid metabolism in patients with schizophrenia: A randomized, double-blind, placebo-controlled clinical trial. PSYCHIATRY RESEARCH.2022.

（2） Weiliang Yang# , Yuting Wang #, Wen Qin , Meijuan Li, Huan Mao, Chi Zhou , Xueying Liu, Jie Li*.Abnormal dynamic functional network connectivity in first-episode, drug-naïve patients with major depressive disorder. J Affect Disord. 2022.

（3） Shen Li , Dachun Chen , Meihong Xiu , Jie Li , Xiang Yang Zhang. Prevalence and clinical correlates of impaired glucose tolerance in first-episode versus chronic patients with schizophrenia. Early Interv Psychiatry. 2022.

（4） Zhonggang Wang # , Tao Li # , Shuhua Li # , Kunkun Li , Xianfei Jiang , Chen Wei , Lei Yang , Haiyan Cao, Shen Li , Jie Li.The prevalence and clinical correlates of medical disorders comorbidities in patients with bipolar disorder. BMC Psychiatry. 2022.

（5） Yeqing Dong # , Tongxin Li # , Zhonghui Ma # , Chi Zhou , Xinxu Wang, Jie Li.HSPA1A, HSPA2, and HSPA8 Are Potential Molecular Biomarkers for Prognosis among HSP70 Family in Alzheimer's Disease. Disease Markers.2022.

（6） Weiliang Yang , Xuexin Xu , Chunxiang Wang , Yongying Cheng, Yan Li, Shuli Xu, Jie Li .Alterations of dynamic functional connectivity between visual and executive-control networks in schizophrenia. Brain Imaging And Behavior.2022.

（7） Lijun Chu, Xia Sun, Xiaoju Jia, Dazhi Li, Ping Gao, Yong Zhang , Jie Li .The Relationship Among BDNF Val66Met Polymorphism, Plasma BDNF Level, and Trait Anxiety in Chinese Patients With Panic Disorder. Frontiers in Psychiatry.2022.

（8） Haiyan Cao , Yongjie Zhou , Tao Li, Cong Yao, Weiliang Yang, Siying Kong, Yanyan Wang, Baoping Yu, Qingyan Jiao, Yun Sun, Xiaoju Jia, Yuting Wang, Zhonggang Wang, Xiangyang Zhang, Jie Li*. The Prevalence, Risk Factors and Clinical Correlates of QTc Prolongation in Chinese Hospitalized Patients With Chronic Schizophrenia. Front Psychiatry. 2021. 

（9） Yuying Qiu#, Meijuan Li#, Yonghui Zhang,Ying Liu a,Yongping Zhao, Jing Zhang,Qiong Jia, Jie Li*. Berberine treatment for weight gain in patients with schizophrenia by regulating leptin rather than adiponectin. ASIAN JOURNAL OF PSYCHIATRY.2021.

（10） Haiyan Cao#, Shen Li#, Ying Gao, Yanyan Ma, Lili Wang, Bing Chen, Rui Jiang,Yuan Zhang, Weidong Li*, Jie Li*. EPB41L4A and LEP gene polymorphisms are associated with antipsychotic-induced QTc interval prolongation in Han Chinese. PSYCHIATRY RESEARCH. 2020.

（11） Chenghao Yang , Ilja M Nolte , Yanyan Ma, Xuguang An, Fokko J Bosker , Jie Li* .The associations of CNR1 SNPs and haplotypes with vulnerability and treatment response phenotypes in Han Chinese with major depressive disorder: A case-control association study Molecular Genetics & Genomic Medicine. Mol Genet Genomic Med. 2021.

（12） Zhonggang Wang, Yuying Cao, Yaya Zhu, Kunkun Li, Xianfei Jiang, Chuanjun Zhuo, Patrick Triplett, Jie Li*. Differences in Demographic and Clinical Characteristics of Patients With Depressive vs. Manic First Episode of Bipolar Disorder. Frontiers in Psychiatry.2021.

（13） Yuting Wang#, Nanage Guobule, Meijuan Li, Jie Li*. The correlation of facial emotion recognition in patients with drug-naive depression and suicide ideation. JOURNAL OF AFFECTIVE DISORDERS. 2021.

（14） Meijuan Li#, Yuying Qiu#, Zhang Jing Zhang, Yonghui Zhang, Ying Liu, Yongping Zhao, Qiong Jia, Xiaoduo Fan*, Jie Li*. Improvement of adjunctive berberine treatment on negative symptoms in patients with schizophrenia. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE.2022.

（15） Shen Li,Yibo Li, Hao Lv, Rui Jiang, Peng Zhao, Xin Zheng, Lili Wang,Jie Li*, Fuqiang Mao* The prevalence and correlates of burnout among Chinese preschool teachers. BMC Public Health.2020.

（16） Zhang, JJ＃ ;Tian, HJ＃;Li, J＃;Ji, SZ;Chen, SL;Zhu, JJ;Jiang, DG ;Wang, LN;Li, GY ;Chen, M ;Wang, WQ ;Lin, XD ;Zhuo, CJ. Ketamine plus propofbi-electroconvulsive therapy (ECT) transiently improves the antidepressant effects and the associated brain functional alterations in patients with propofbl-ECT-resistant depression. Psychiatry Research.2020.

（17） Tang Y, Mi P, Li M, Zhang S,Li J*, Feng X*. Environmental level of the antidepressant venlafaxine induces behavioral disorders through cortisol in zebrafish larvae (Danio rerio). Neurotoxicol Teratol.2020.

（18） Yun Sun , Jie Li*, Xinjun Zhang , Qingyan Jiao , Shutong Yang and Lijie Ji Case Report: Parasomnia Overlap Disorder Induced by Obstructive Sleep Hypopnea Apnea Syndrome: A Case Report and Literature Review. Frontiers in neuroscience.2020.

（19） Jie Li*, Shen LiNeuropsychopharmacotherapy and the Differential Diagnostic Approaches in China & Neuropsychopharmacotherapy: Differential Doses Regimes in China. Chapters in Neuropsychopharmacotherapy Springer.2020.

（20） Yang C, Si J, Suo L, Zhang Y, Li J* Chronic exposure to fluoxetine of female mice before mating causes impaired stress resilience in female offspring. J Neural Transm (Vienna). 2019.

（21） Jingjing Zhu, Weihong Hou, Yong Xu, Feng Ji, Guowei Wang, Ce Chen, Chongguang Lin, Xiodong Lin, Jie Li*, Chuanjun Zhuo*, Mingjng Shao* Antipsychotic drugs and sudden cardiac death: A literature review of thechallenges in the prediction, management, and future steps. Psychiatry Research.2019.

（22） Yang C, Bosker FJ, Li J*, Schoevers RA. N-acetylcysteine as add-on to antidepressant medication in therapy  refractorymajor  depressivd disorder patients with increased inflammatory activity: study protocol of a double-blind randomized placebo-controlled trial. BMC Psychiatry. 2018.

（23） Shen Li,Ying Gao, Hao Lv, Miaomiao Zhang, Lili Wang, Rui Jiang, Chengai Xu, Xueshi Wang, Ming Gao, Yukun He,Jie Li*, Wei-Dong Li*. T4 and waist:hip ratio as biomarkers of antipsychotic-induced weight gain in Han Chinese inpatients with schizophrenia. Psychoneuroendocrinology.2018.

1.天津市自然科学基金，应用基础重点项目，22JCZDJC00110，基于“肠道菌群-肠-脑”轴研究黄连素改善精神分裂症认知损害的机制，2023.2至2025.9，在研，40万，主持.

2.天津市卫生健康科技项目，TJWJ2022XK039，血浆外泌体microRNAs在首发精神分裂症认知损害中的作用及机制，2022.7至2025.6，在研，49.18万，主持.

3.国家自然科学基金，国家重大科研仪器研制项目，62027812,面向清醒动物脑科学研究的机器人化主动膜片钳系统,2021.01至2025.12，在研，77.51万，参与.

已完成项目：

1.天津市科学技术委员会，慢性病防治科技重大专项，2017ZXMFSY00070，抗精神病药治疗精神分裂症的药物基因组学及药物表观组学研究，2017-01 至 2021-09，已结题，50万元，主持.

2.天津市科学技术局，天津市自然科学基金一般项目，16JCYBJC2420，MEGF10、MERTK蛋白及星形胶质细胞在应激抗性中的作用，2016-04 至 2019-03，已结题，10 万元，主持.

3.天津市卫生行业重点公关，13KG118，炎症与氧化应激在抑郁症中的作用机制研究， 2013-06至2016-05，已结题，20 万元，主持. 

2020年获中华医学科技二等奖。

1.中华医学会行为医学分会第5,6届常务委员、副秘书长

2.中华医学会精神医学分会第8届委员

3.中国心理卫生协会 第7届常务理事

4.天津市医学会精神病学分会主任委员

5.天津市医学会行为医学分会主任委员

6.《中华行为医学与脑科学》杂志编委

7.《中国健康心理学》杂志编委

8.《神经疾病与精神卫生》杂志编委

9.《四川精神卫生》杂志编委

10.《Comprehensive Psychiatry》杂志编委

11.《World Journal of Psychiatry》杂志编委