男，1969年12月出生，中国共产党党员，呼吸科行政主任，呼吸科党支部书记。

儿童呼吸、感染、变态反应性疾病，儿童结核病

1: ESI高被引论文 Zhang T, Cui X, Zhao X, Wang J, Zheng J, Zheng G, Guo W, Cai C, He S, Xu Y. Detectable SARS-CoV-2 viral RNA in feces of three children during recovery period of COVID-19 pneumonia. J Med Virol. 2020 Jul;92(7):909-914. doi:10.1002/jmv.25795. Epub 2020 Apr 15. PMID: 32222992; PMCID: PMC7228213.

2: Zhu Z, Zhang T, Guo W, Ling Y, Tian J, Xu Y. Clinical characteristics of refractory mycoplasma pneumoniae pneumonia in children treated with glucocorticoid pulse therapy. BMC Infect Dis. 2021 Jan 28;21(1):126. doi:10.1186/s12879-021-05830-4. PMID: 33509121; PMCID: PMC7844890.

3: Shen F, Dong C, Zhang T, Yu C, Jiang K, Xu Y, Ning J. Development of a Nomogram for Predicting Refractory <i>Mycoplasma pneumoniae</i> Pneumonia in Children. Front Pediatr. 2022 Feb 25;10:813614. doi: 10.3389/fped.2022.813614.PMID: 35281240; PMCID: PMC8916609.

4: Zhao Y, Zhang T, Yang N, Xu Y, Guo W. Efficacy and safety of CO₂cryotherapy in the treatment of infants with tracheobronchial tuberculosis.Front Pediatr. 2022 Oct 10;10:984738. doi: 10.3389/fped.2022.984738. PMID:36299689; PMCID: PMC9591804.

5: Dong H, Dong L, Yu Y, Fu J, Chen X, Xu Y, Cai C. Cryptogenic massive hemoptysis caused by bronchial artery-pulmonary artery fistula in a 12-year-old boy: A case report and literature review. Pediatr Pulmonol. 2022 May;57(5):1202-1208. doi: 10.1002/ppul.25872. Epub 2022 Mar 9. PMID: 35229484.

6: Zhang T, Han C, Guo W, Ning J, Cai C, Xu Y. Case Report: Clinical Analysis of Fulminant <i>Mycoplasma pneumoniae</i> Pneumonia in Children. Front Pediatr.2021 Dec 9;9:741663. doi: 10.3389/fped.2021.741663. PMID: 34956973; PMCID:PMC8696182.

7: Zhang T, Zheng J, Wang H, Xu Y, Ning J, Cai C. Case Report: Cardiac Multiple Thrombus and Pulmonary Embolism Associated With Mycoplasma Pneumonia Infection in a Child. Front Pediatr. 2022 Jul 18;10:959218. doi: 10.3389/fped.2022.959218.PMID: 35923784; PMCID: PMC9339891.

8: Dong C, Shen F, Dong H, Dong L, Fu Y, Xu Y, Ning J. Community-acquired Pseudomonas aeruginosa pneumonia manifested by bloody pleural effusion in a previously healthy infant: A case report. J Clin Lab Anal. 2022 Jun;36(6):e24466. doi: 10.1002/jcla.24466. Epub 2022 May 13. PMID: 35561264;PMCID: PMC9169175.

9: Zhao L, Zhang T, Cui X, Zhao L, Zheng J, Ning J, Xu Y, Cai C. Development and validation of a nomogram to predict plastic bronchitis in children with refractory Mycoplasma pneumoniae pneumonia. BMC Pulm Med. 2022 Jun 27;22(1):253.doi: 10.1186/s12890-022-02047-2. PMID: 35761218; PMCID: PMC9235233.

10: Ling Y, Si M, Niu Y, Han Y, Xu Y. The predictive value of impulse oscillometry for asthma exacerbations in childhood: A systematic review and meta-analyses. Pediatr Pulmonol. 2021 Jul;56(7):1850-1856. doi:10.1002/ppul.25374. Epub 2021 Mar 23. PMID: 33756052; PMCID: PMC8251639.

11: Han C, Zhang T, Zheng J, Jin P, Zhang Q, Guo W, Xu Y. Analysis of the risk factors and clinical features of Mycoplasma pneumoniae pneumonia with embolism in children: a retrospective study. Ital J Pediatr. 2022 Aug 20;48(1):153. doi:10.1186/s13052-022-01344-0. PMID: 35987653; PMCID: PMC9391649.

12: Ling Y, Zhang T, Guo W, Zhu Z, Tian J, Cai C, Xu Y. Identify clinical factors related to Mycoplasma pneumoniae pneumonia with hypoxia in children. BMC Infect Dis. 2020 Jul 22;20(1):534. doi: 10.1186/s12879-020-05270-6. PMID:32698769; PMCID: PMC7374650.

13: Han C, Zhang T, Zhao Y, Dong L, Li X, Zheng J, Guo W, Xu Y, Cai C.Successful treatment of pleural empyema and necrotizing pneumonia caused by methicillin-resistant <i>Staphylococcus aureus</i> infection following influenza A virus infection: A case report and literature review. Front Pediatr. 2022 Aug26;10:959419. doi: 10.3389/fped.2022.959419. PMID: 36090578; PMCID: PMC9462453.

14: Zheng J, Zhang T, Guo W, Zhou C, Cui X, Gao L, Cai C, Xu Y. Integrative Analysis of Multi-Omics Identified the Prognostic Biomarkers in Acute Myelogenous Leukemia. Front Oncol. 2020 Dec 10;10:591937. doi: 10.3389/fonc.2020.591937. PMID: 33363022; PMCID: PMC7758482.

15: Ling Y, Ning J, Xu Y. Explore the Predictive Value of Peripheral Blood Cell Parameters in Refractory <i>Mycoplasma pneumoniae</i> Pneumonia in Children Over 6 Years Old. Front Pediatr. 2021 Nov 12;9:659677. doi: 10.3389/fped.2021.659677.PMID: 34869089; PMCID: PMC8633951.

16: Zheng J, Dong H, Zhang T, Ning J, Xu Y, Cai C. Development and Validation of a Novel Gene Signature for Predicting the Prognosis of Idiopathic Pulmonary Fibrosis Based on Three Epithelial-Mesenchymal Transition and Immune-Related Genes. Front Genet. 2022 Apr 26;13:865052. doi: 10.3389/fgene.2022.865052. PMID:35559024; PMCID: PMC9086533.

17: Zheng J, Zhang T, Guo W, Zhou C, Cui X, Gao L, Cai C, Xu Y. Integrative Analysis of Multi-Omics Identified the Prognostic Biomarkers in Acute Myelogenous Leukemia. Front Oncol. 2020 Dec 10;10:591937. doi:10.3389/fonc.2020.591937. PMID: 33363022; PMCID: PMC7758482.

18: Ling Y, Ning J, Xu Y. Explore the Predictive Value of Peripheral Blood Cell Parameters in Refractory <i>Mycoplasma pneumoniae</i> Pneumonia in Children Over 6 Years Old. Front Pediatr. 2021 Nov 12;9:659677. doi: 10.3389/fped.2021.659677.PMID: 34869089; PMCID: PMC8633951.

19: Cui X, Zhao Z, Zhang T, Guo W, Guo W, Zheng J, Zhang J, Dong C, Na R, Zheng L, Li W, Liu Z, Ma J, Wang J, He S, Xu Y, Si P, Shen Y, Cai C. A systematic review and meta-analysis of children with coronavirus disease 2019 (COVID-19). J Med Virol. 2021 Feb;93(2):1057-1069. doi: 10.1002/jmv.26398. Epub 2020 Sep 28.PMID: 32761898; PMCID: PMC7436402.

20: ESI高被引论文 Zhang T, Cui X, Zhao X, Wang J, Zheng J, Zheng G, Guo W, Cai C, He S, Xu Y. Detectable SARS-CoV-2 viral RNA in feces of three children during recovery period of COVID-19 pneumonia. J Med Virol. 2020 Jul;92(7):909-914. doi:10.1002/jmv.25795. Epub 2020 Apr 15. PMID: 32222992; PMCID: PMC7228213.

21: Zhu Z, Zhang T, Guo W, Ling Y, Tian J, Xu Y. Clinical characteristics of refractory mycoplasma pneumoniae pneumonia in children treated with glucocorticoid pulse therapy. BMC Infect Dis. 2021 Jan 28;21(1):126. doi:10.1186/s12879-021-05830-4. PMID: 33509121; PMCID: PMC7844890.

22: Shen F, Dong C, Zhang T, Yu C, Jiang K, Xu Y, Ning J. Development of a Nomogram for Predicting Refractory <i>Mycoplasma pneumoniae</i> Pneumonia in Children. Front Pediatr. 2022 Feb 25;10:813614. doi: 10.3389/fped.2022.813614.PMID: 35281240; PMCID: PMC8916609.

23: Zhao Y, Zhang T, Yang N, Xu Y, Guo W. Efficacy and safety of CO₂cryotherapy in the treatment of infants with tracheobronchial tuberculosis.Front Pediatr. 2022 Oct 10;10:984738. doi: 10.3389/fped.2022.984738. PMID:36299689; PMCID: PMC9591804.

24: Dong H, Dong L, Yu Y, Fu J, Chen X, Xu Y, Cai C. Cryptogenic massive hemoptysis caused by bronchial artery-pulmonary artery fistula in a 12-year-old boy: A case report and literature review. Pediatr Pulmonol. 2022 May;57(5):1202-1208. doi: 10.1002/ppul.25872. Epub 2022 Mar 9. PMID: 35229484.

25: Zhang T, Han C, Guo W, Ning J, Cai C, Xu Y. Case Report: Clinical Analysis of Fulminant <i>Mycoplasma pneumoniae</i> Pneumonia in Children. Front Pediatr.2021 Dec 9;9:741663. doi: 10.3389/fped.2021.741663. PMID: 34956973; PMCID:PMC8696182.

26: Zhang T, Zheng J, Wang H, Xu Y, Ning J, Cai C. Case Report: Cardiac Multiple Thrombus and Pulmonary Embolism Associated With Mycoplasma Pneumonia Infection in a Child. Front Pediatr. 2022 Jul 18;10:959218. doi: 10.3389/fped.2022.959218.PMID: 35923784; PMCID: PMC9339891.

27: Dong C, Shen F, Dong H, Dong L, Fu Y, Xu Y, Ning J. Community-acquired Pseudomonas aeruginosa pneumonia manifested by bloody pleural effusion in a previously healthy infant: A case report. J Clin Lab Anal. 2022 Jun;36(6):e24466. doi: 10.1002/jcla.24466. Epub 2022 May 13. PMID: 35561264;PMCID: PMC9169175.

28: Zhao L, Zhang T, Cui X, Zhao L, Zheng J, Ning J, Xu Y, Cai C. Development and validation of a nomogram to predict plastic bronchitis in children with refractory Mycoplasma pneumoniae pneumonia. BMC Pulm Med. 2022 Jun 27;22(1):253.doi: 10.1186/s12890-022-02047-2. PMID: 35761218; PMCID: PMC9235233.

29: Ling Y, Si M, Niu Y, Han Y, Xu Y. The predictive value of impulse oscillometry for asthma exacerbations in childhood: A systematic review and meta-analyses. Pediatr Pulmonol. 2021 Jul;56(7):1850-1856. doi:10.1002/ppul.25374. Epub 2021 Mar 23. PMID: 33756052; PMCID: PMC8251639.

30: Han C, Zhang T, Zheng J, Jin P, Zhang Q, Guo W, Xu Y. Analysis of the risk factors and clinical features of Mycoplasma pneumoniae pneumonia with embolism in children: a retrospective study. Ital J Pediatr. 2022 Aug 20;48(1):153. doi:10.1186/s13052-022-01344-0. PMID: 35987653; PMCID: PMC9391649.

31: Ling Y, Zhang T, Guo W, Zhu Z, Tian J, Cai C, Xu Y. Identify clinical factors related to Mycoplasma pneumoniae pneumonia with hypoxia in children. BMC Infect Dis. 2020 Jul 22;20(1):534. doi: 10.1186/s12879-020-05270-6. PMID:32698769; PMCID: PMC7374650.

32: Han C, Zhang T, Zhao Y, Dong L, Li X, Zheng J, Guo W, Xu Y, Cai C.Successful treatment of pleural empyema and necrotizing pneumonia caused by methicillin-resistant <i>Staphylococcus aureus</i> infection following influenza A virus infection: A case report and literature review. Front Pediatr. 2022 Aug26;10:959419. doi: 10.3389/fped.2022.959419. PMID: 36090578; PMCID: PMC9462453.

33: Zheng J, Zhang T, Guo W, Zhou C, Cui X, Gao L, Cai C, Xu Y. Integrative Analysis of Multi-Omics Identified the Prognostic Biomarkers in Acute Myelogenous Leukemia. Front Oncol. 2020 Dec 10;10:591937. doi: 10.3389/fonc.2020.591937. PMID: 33363022; PMCID: PMC7758482.

34: Ling Y, Ning J, Xu Y. Explore the Predictive Value of Peripheral Blood Cell Parameters in Refractory <i>Mycoplasma pneumoniae</i> Pneumonia in Children Over 6 Years Old. Front Pediatr. 2021 Nov 12;9:659677. doi: 10.3389/fped.2021.659677.PMID: 34869089; PMCID: PMC8633951.

35: Zheng J, Dong H, Zhang T, Ning J, Xu Y, Cai C. Development and Validation of a Novel Gene Signature for Predicting the Prognosis of Idiopathic Pulmonary Fibrosis Based on Three Epithelial-Mesenchymal Transition and Immune-Related Genes. Front Genet. 2022 Apr 26;13:865052. doi: 10.3389/fgene.2022.865052. PMID:35559024; PMCID: PMC9086533.

36: Zheng J, Zhang T, Guo W, Zhou C, Cui X, Gao L, Cai C, Xu Y. Integrative Analysis of Multi-Omics Identified the Prognostic Biomarkers in Acute Myelogenous Leukemia. Front Oncol. 2020 Dec 10;10:591937. doi:10.3389/fonc.2020.591937. PMID: 33363022; PMCID: PMC7758482.

37: Ling Y, Ning J, Xu Y. Explore the Predictive Value of Peripheral Blood Cell Parameters in Refractory <i>Mycoplasma pneumoniae</i> Pneumonia in Children Over 6 Years Old. Front Pediatr. 2021 Nov 12;9:659677. doi: 10.3389/fped.2021.659677.PMID: 34869089; PMCID: PMC8633951.

38: Cui X, Zhao Z, Zhang T, Guo W, Guo W, Zheng J, Zhang J, Dong C, Na R, Zheng L, Li W, Liu Z, Ma J, Wang J, He S, Xu Y, Si P, Shen Y, Cai C. A systematic review and meta-analysis of children with coronavirus disease 2019 (COVID-19). J Med Virol. 2021 Feb;93(2):1057-1069. doi: 10.1002/jmv.26398. Epub 2020 Sep 28.PMID: 32761898; PMCID: PMC7436402.

[1] 董春娟,徐勇胜,宁静,等. 溶栓治疗儿童肺炎支原体肺炎并心腔血栓及肺栓塞2例[J]. 中华实用儿科临床杂志,2022,37(19):1495-1497.DOI:10.3760/cma. j.cn101070- 20211109 -01332.

[2] 董春娟,宁静,徐勇胜. 肺炎支原体肺炎患儿并发血管栓塞机制研究进展[J]. 山东医药,2022,62(8):112-115. DOI:10.3969/j.issn.1002-266X.2022.08.028.

[3] 赵艺迪,张同强,刘福军,等. CO2冷冻联合钳夹治疗婴幼儿淋巴结瘘型气管支气管结核的疗效和安全性研究[J]. 中国防痨杂志,2022,44(8):827-834. DOI:10.19982/j.issn. 1000-6621.20220114.

[4] 田娇,徐勇胜. 呼吸音分析在儿童支气管哮喘中的研究进展[J]. 中国医学科学院学报,2021,43(5):833-839. DOI:10.3881/j.issn.1000-503X.11953.

[5] 王维,张同强,侯梦珠,等. 天津地区儿童感染呼吸道病原菌组成及其临床特征[J]. 中华儿科杂志,2021,59(11):949-956. DOI:10.3760/cma.j.cn112140-20210331-00276.

[6] 沈芳芳,徐勇胜,宁静,等. NCF2基因复合杂合突变导致慢性肉芽肿病1例并文献复习 [J]. 中华实用儿科临床杂志,2021,36(10):776-778. DOI:10.3760/cma.j.cn101070 -20200415-00646.

[7] 姜姝婷,胡思源,李新民,等. 黄龙止咳颗粒治疗儿童咳嗽变异性哮喘多中心随机对照临床研究[J]. 中国中医药信息杂志,2021,28(5):104-109. DOI:10.19879/j.cnki.1005-5304. 202011345.

[8] 于长江,徐勇胜. 儿童呼吸道病毒感染治疗进展[J]. 国际儿科学杂志,2021,48(1): 43 -46 DOI:10.3760/cma.j.issn.1673-4408.2021.01.011.

[9] 李小乐,郭伟,徐勇胜. 万古霉素致儿童药物超敏反应综合征文献病例分析[J]. 药物不良反应杂志,2021,23(1):10-14. DOI:10.3760/cma.j.cn114015-20200706-00744.

[10] 朱珍丽,凌瑶瑶,徐勇胜. 不同剂量糖皮质激素治疗小儿难治性肺炎支原体肺炎的研究进展[J]. 国际儿科学杂志,2020,47(11):792-795. DOI:10.3760/cma.j.issn.1673-4408. 2020.11.010.

[11] 朱珍丽,凌瑶瑶,徐勇胜. 抗胆碱能药物在儿童哮喘治疗中的研究进展[J]. 国际儿科学杂志,2020,47(8):561-564. DOI:10.3760/cma.j.issn.1673-4408.2020.08.011.

[12] 沈芳芳,宁静,徐勇胜,等. 儿童冠状病毒感染的研究进展[J]. 临床荟萃,2020,35 (7):667-672. DOI:10.3969/j.issn.1004-583X.2020.07.018.

[13] 张同强,郑家峰,徐勇胜. 暴发性肺炎支原体肺炎的临床特点及治疗[J]. 医学信息,2020,33(13):26-29,34. DOI:10.3969/j.issn.1006-1959.2020.13.008.

[14] 韩宇琦,徐勇胜. 支气管肺发育不良潮气肺功能监测应用进展[J]. 中国实用儿科杂志,2022,37(3):228-231,235. DOI:10.19538/j.ek2022030613.

[15] 李小乐,郭伟,宁静,等. 头孢菌素致儿童DRESS综合征2例[J]. 中国医院药学杂志,2022,42(6):673-674. DOI:10.13286/j.1001-5213.2022.06.20.

[16] 魏瑞丽,吕健,李新民,等. 基于儿童社区获得性肺炎评价安儿宁颗粒减少抗生素应用的随机、双盲单模拟、安慰剂平行对照、多中心临床试验[J]. 中国实验方剂学杂志,2022, 28(19):105-114. DOI:10.13422/j.cnki.syfjx.20221994.

[17] 薛燕,许俐,党利亨,等. 甲型和乙型流感病毒感染患儿淋巴细胞亚群和IL-6的表达[J]. 江苏医药,2021,47(7):689-692. DOI:10.19460/j.cnki.0253-3685.2021.07.011.

[18] 徐勇胜. 间质性肺疾病患儿肺功能改变的特征[J]. 中国实用儿科杂志,2021, 36 (6):416-420. DOI:10.19538/j.ek2021060604.

[19] 杜丽娜,杨燕,牟青慧,等. 清宣止咳颗粒治疗儿童感冒风热证临床研究[J]. 中华中医药杂志,2021,36(2):1157-1160.

[20] 田娇,宁静,徐勇胜. 微小RNA(microRNA)与儿童支气管哮喘关系的研究进展[J]. 细胞与分子免疫学杂志,2021,37(5):460-466.

[21] 田娇,宁静,徐勇胜. 儿童支气管哮喘差异表达微小RNA(miRNA)的生物信息学分析[J]. 细胞与分子免疫学杂志,2021,37(10):923-931.

[22] 王文玉,徐勇胜,郭伟,等. 预后良好的甲型流感病毒合并细菌感染致坏死性肺炎1例报告[J]. 中国实用儿科杂志,2020,35(12):990-992. DOI:10.19538/j.ek2020120616.

[23] 孙娜,徐勇胜. 1例儿童肺炎支原体肺炎合并肺栓塞临床分析[J]. 儿科药学杂志,2020, 26(6):24-26. DOI:10.13407/j.cnki.jpp.1672-108X.2020.06.008.

1.  KL-6应用于间质性肺疾病血清学检测中的数据库构建及数据分析。2021KYSHX 00609省部级

2.  儿童呼吸道感染性疾病病原体快速诊断及抗菌药物精准治疗研究。20JCZXJC00170 省部级

3.  小儿肺炎传承创新平台建设项目。2020-1  省部级

4.  国家新药研发项目临床试验，一项在呼吸道合胞病毒感染的住院婴幼儿中评价多次口服AK0529的有效性、安全性、耐受性、药代动力学特征和抗病毒作用的随机、双盲、安慰剂对照的研究（AK0529-2003）。

5.  国家新药研发项目临床试验，一项在呼吸道合胞病毒感染的2至5岁住院患儿中评价多次口服 AK0529 肠溶胶囊药代动力学、安全性和疗效的开放、单臂研究。AK0529-2004  横向项目  

6.  基于儿童社区获得性肺炎评价安儿宁颗粒减少抗生素应用的随机、双盲单模拟、安慰剂平行对照、多中心临床试验 中国中医科学院中医临床基础研究所：中成药减少抗生素使用项目   Z0546

1)  2018年中国防痨协会首届最美防痨人

2)  2021年天津市第六届“好医生”

(1) 中华医学会儿科分会呼吸学组委员

(2) 中华医学会结核病分会儿童结核病专业委员会常务委员

(3) 中华医学会儿科分会呼吸学组肺功能协作组副组长

(4) 中国医师协会变态反应医师分会委员

(5) 中国防痨协会理事

(6) 天津市医学会结核病分会副主任委员

(7) 天津市医学会变态反应学分会副主任委员

(8) 天津市卫健委儿科质量控制中心副主任

(9) 天津市卫健委毕业后教育委员会住培质控组委员