Brief Introduction:

Prof. Zhang joined Tianjin University as in 2016. He received his Ph.D. from Tianjin University and achieve postdoc research at Stanford University in Prof. Hongjie Dai's lab. His research interest involves in Biomaterials, Nanomedicine and NIR-II imaging. He is a Chief Scientist of the National Key Research and Development Program of China. He was selected as the National Young Talent Program. He has been honored as a Highly Cited Researcher by Clarivate Analytics (2021) and an Elsevier Highly Cited Scholar (2020-2022) and revieved the Tianjin Science Fund for Distinguished Young Scholars Award.

Academic Achievements:

Prof. Zhang has long been engaged in biomaterials, nanobiomedicine and optical imaging. He proposed the concept of 'clusterzyme' to achieve efficient intervention in acute nerve trauma (Nat. Commun. 2021). His team constructed artificial enzyme sutures and gels that surpass the reaction affinity of natural enzymes to achieve the regulation of subacute neurotrauma (Nat. Commun. 2022). They discovered ultrafast artificial enzymes that achieve highly effective suppression of chronic neurotrauma and neurocognitive improvements. (Sci. Adv. 2021). In addition, bioactive NIR-II cluster were also designed to achieve efficient pathological monitoring (Matter 2024; Sci. Adv. 2023; Adv. Mater. 2019). Furthermore, a new generation of highly compatible artificial enzyme electrode was constructed to record high-resolution neural signals (Adv. Mater. 2024). Prof. Zhang has published more than 100 papers including Nature Communications, Science Advances, Advanced Materials, Nano Letters, ACS Nano, Coordination Chemistry Reviews, Pharmacological Sciences etc. The total citations exceeds 12,000, including 1 hot paper and 15 ESI Highly Cited papers.

Honors & Awards:

Chief Scientist of the National Key Research and Development Program of China (2021)

National Youth Talent Plan Project (2019)

Clarivate "Highly Cited Researchers" (2021)

Elsevier China Highly Cited Scholar (2020-2022)

Chinese Society of Toxicology Outstanding Youth Science and Technology Award (2022)

Tianjin Outstanding Youth Fund (2021)

Tianjin 131 Talent Plan (2017)

Tianjin University Beiyang Young Scholar (2016)

Tianjin Youth Outstanding Scientific and Technological Talents Program (2015)

Chinese Academy of Medical Sciences and Peking Union Medical College’s "Peking Union Medical College Rising Star" (2012)

Selected Plulications:

1. Huizhen Ma, Ling Liu, Hua He, Si Sun, Shuyu Yang, You Huang, Yuan Li, Kexin Tan, Haile Liu, Shuhu Liu, Yonghui Li, Changlong Liu, Pengfei Liu, Hao Wang, Xiao-Dong Zhang*, Atomically precise Ag clusters for intelligent NIR-II imaging, Matter, 2024, https://www.cell.com/matter/abstract/S2590-2385(24)00065-1

2. Shuangjie Liu, Yang Wang, Yue Zhao, Ling Liu, Si Sun, Shaofang Zhang, Haile Liu, Shuhu Liu, Yonghui Li, Fan Yang, Menglu Jiao, Xinyu Sun, Yuqin Zhang, Renpeng Liu, Xiaoyu Mu, Hao Wang, Shu Zhang, Jiang Yang, Xi Xie, Xiaojie Duan, Jianning Zhang, Guosong Hong, Xiao-Dong Zhang,* Dong Ming*, A Nanozyme-Based Electrode for High-Performance Neural Recording, Advanced Materials, 2024, 2304297,

https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.202304297

3. Huizhen Ma, Xiaoning Zhang, Ling Liu, You Huang, Si Sun, Ke Chen, Qi Xin, Pengfei Liu, Yuxing Yan, Yili Wang, Yuan Li, Haile Liu, Ruoli Zhao, Kexin Tan, Xinzhu Chen, Xun Yuan, Yonghui Li, Ying Liu, Haitao Dai, Changlong Liu, Hao Wang,* Xiao-Dong Zhang*, Bioactive NIR-II gold clusters for three-dimensional imaging and acute inflammation inhibition, Science Advances, 2023, https://www.science.org/doi/full/10.1126/sciadv.adh7828

4. Shaofang Zhang, Yonghui Li, Si Sun, Ling Liu, Xiaoyu Mu, Shuhu Liu, Menglu Jiao, Xinzhu Chen, Ke Chen, Huizhen Ma, Tuo Li, Xiaoyu Liu, Hao Wang, Jianning Zhang, Jiang Yang & Xiao-Dong Zhang*, Single-atom nanozymes catalytically surpassing naturally occurring enzymes as sustained stitching for brain trauma, Nature Communications, 2022, https://www.nature.com/articles/s41467-022-32411-z

5. Xiaoyu Mu, Junying Wang, Hua He, Qifeng Li, Bing Yang, Junhui Wang, Haile Liu, Yalong Gao, Lufei Ouyang, Si Sun, Qinjuan Ren, Xinjian Shi, Wenting Hao, Qiaoman Fei, Jiang Yang, Lulin Li, Ryan Vest, Tony Wyss-Coray, Jian Luo, and Xiao-Dong Zhang*, An Oligomeric Semiconducting Nanozyme with Ultrafast Electron Transfers Alleviates Acute Brain Injury, Science Advances, 2021, https://www.science.org/doi/full/10.1126/sciadv.abk1210

6. Haile Liu, Yonghui Li, Si Sun, Qi Xin, Shuhu Liu, Xiaoyu Mu, Xun Yuan, Ke Chen, Hao Wang, Kalman Varga, Wenbo Mi, Jiang Yang & Xiao-Dong Zhang*, Catalytically potent and selective clusterzymes for modulation of neuroinflammation through single-atom substitutions, Nature Communications, 2021, https://www.nature.com/articles/s41467-020-20275-0.

7. Haile Liu, Guosong Hong, Zhentao Luo, Junchi Chen, Junlei Chang, Ming Gong, Hua He, Jiang Yang, Xun Yuan, Lulin Li, Xiaoyu Mu, Junying Wang, Wenbo Mi, Jian Luo, Jianping Xie*, and Xiao-Dong Zhang *, Atomic Precision Gold Clusters for NIR-II Imaging, Advanced Materials, 2019. https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201901015