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樊毫军

职称/职务:教授
办公室:天津大学应急医学研究院10号东配楼
邮箱:fanhj@tju.edu.cn

 

个人简介

 

樊毫军,天津大学应急医学研究院院长,智能生命支持技术装备工程中心主任。医学博士,主任医师,教授,博士生导师。“拯救生命计划”(SLP)公益项目发起人。恪守天津大学“实事求是”的校训,立足救援实战搞科研,助力国家重大需求难题破解。主要致力于智能心肺支持技术装备,地震挤压伤、火灾吸入伤救治的研究工作。先后承担国家“十三五”、“十四五”重点研发计划、科技部重点支撑项目、国家卫计委重点专项等多项重点项目。获国家科技进步二等奖2项,武警科技进步一等奖2项,天津市科技进步一等奖2项等。获武警部队科技拔尖人才,首都“第二届健康卫士”,中国科协“求是杰出青年奖”,2022年天津科普大使。

 

研究方向

 

致力于应急医学领域心肺支持、地震挤压伤、火灾吸入伤研究。

 

社会学术兼职

 

国家应急管理部医学救援重点实验室  常务副主任

国家卫健委  国家救援队建设指导专家

中国医师协会急救复苏和灾难医学分会  主任委员

中华医学会灾难医学分会   候任主委

中国医学救援协会生命支持分会  会长

世界灾难与急救医学协会  国际执委会委员

哈佛大学灾难医学训练中心  兼职讲师

天津市救援医学学会  常务副会长

天津市灾害救援医学创新人才团队   负责人

 

工作经历

 

先后担任中国武警总医院呼吸重症科副主任医师,科教科长,武警医学院附属医院医教部副主任,全军救援医学重点实验室常务副主任,大校军衔。

曾作为中国国际救援队医疗队副队长和国家卫健委武警救援队队长,参加阿尔及利亚,印尼海啸,巴基斯坦地震,海地地震,大兴安岭火灾,汶川地震,玉树地震,雅安地震,腺病毒疫情防控、天津港火灾爆炸,安徽水灾等20批次国内外重大救援,荣立二等功1次,三等功2次。

 

代表性学术成果

 

【主要参与完成科研项目】

1.     国家重点研发计划重点专项,2021YFC3002200,灾害事故现场危重症伤员伤情评估与快速诊治关键技术装备,获批经费:3681万元,2021.12-2024.11,首席科学家

2.     国家自然科学基金面上项目,81971878MSCs基于M1/M2-Th17/Treg免疫稳态调控烟雾吸入性肺损伤后炎症反应的机制研究,获批经费:66万元,2020.01-2023.12,主持

3.     国家重点研发计划重点专项子课题,2018YFC1504402-02,联合搜救相关数据与模型集成管理平台的开发,获批经费:128万元,2018.12-2021.12,主持

4.     横向产学研项目,TJUWYY2022002,高端智能急救型ECMO关键技术装备研发,获批经费:3000万元,2022.01-2023.12,主持

5.     温州市重大科技创新攻关项目,ZS2022007,急救型ECMO研发,获批经费:430万元,2023.01-2025.12,主持

6.     国家重点研发计划重点专项子课题,2018YFC1603706-03,重特大自然灾害应急食品供应体系及综合风险防范技术研究,获批经费:115万元,2019.01-2021.12,参加

7.     国家重点研发计划重点专项,2016YFC0802806,灾害环境下人体损伤机理研究与救援防护技术装备研发及应用示范,获批经费:788万元,2016.06-2019.06,参加

8.     国家自然科学基金面上项目,71533008,基于协同学视角下案例推理的巨灾型突发事件医学应急救援风险分析及机制研究,获批经费:230万元2016.01-2020.12,参加

9.     国家自然科学基金面上项目,71473265,基于案例推理的大型医院非常规突发事件应急救援系统研究,获批经费:60万元,2015.01-2018.12,参加

10.  天津市科技计划项目,15ZXLCSY00040MicroRNA在烟雾吸入性肺损伤患者体内差异表达的研究,获批经费:100万元,2015.01-2019.12,主持

 

【代表性论文】

1.     Wenli Li, Yuansen Chen, Duo Li, Xiangyan Meng, Ziquan Liu, Yanqing Liu, Haojun Fan. Hemoadsorption in acute respiratory distress syndrome patients requiring venovenous extracorporeal membrane oxygenation: a systematic review[J]. Respiratory Research, 2024, 25(1):27.

2.     Qianying Lu, Yangfan Liang, Sijia Tian, Jie Jin, Yanmei Zhao, Haojun Fan. Radiation-Induced Intestinal Injury: Injury Mechanism and Potential Treatment Strategies[J]. Toxics, 2023,11(12):1011.

3.     Yue Li, Zhaoying Li, Chunjie Li, Wei Cai, Tao Liu, Ji Li, Haojun Fan, Chunxia Cao. Out-of-hospital cardiac arrest: A data-driven visualization of collaboration, frontier identification, and future trends[J]. Medicine, 2023,102(33).

4.     Duo Li, Yuansen Chen, Bofan Yang, Wenli Li, Yang Xu, Xiangyu Wang, Yanjiao Teng, Yu Luo, Chunli Liu, Jie Shi, Xiaoqin Guo, Yanqing Liu, Qi Lv*, Haojun Fan. Breaking New Ground: Standardizing Rat Models for Crush Syndrome Investigations[J]. 2023.

5.     Qianying Lu, Yangfan Liang, Xiangyan Meng, Yanmei Zhao, Haojun Fan, Shike Hou. The Role of Long Noncoding RNAs in Intestinal Health and Diseases: A Focus on the Intestinal Barrier[J]. Biomolecules, 2023,13(11),1674.

6.     Yao Zixuan, Chen Yuansen, Li Duo, Li Yongnan, Liu Yanqing, Fan Haojun. Hemorrhagic Shock Assessed by Tissue Microcirculatory Monitoring: A Narrative Review[J]. Shock, 2023.

7.     Wei Han, Jinyang Yuan, Rui Li, Le Yang, Jiaqin Fang, Haojun Fan, Shike Hou. Clinical application of a body area network-based smart bracelet for pre-hospital trauma care[J]. Frontiers in Medicine, 2023,10,1190125.

8.     Yu Luo, Chunli Liu, Duo Li, Bofan Yang, Jie Shi, Xiaoqin Guo, Haojun Fan, Qi Lv. Progress in the Diagnostic and Predictive Evaluation of Crush Syndrome. Diagnostics[J]. Diagnostics, 2023,13(19):3039.

9.     Mingyu Shi, Qianying Lu, Yanmei Zhao, Ziling Ding, Sifan Yu, Junfeng Li, Mengjun Ji, Haojun Fan, Shike Hou. miR-223: a key regulator of pulmonary inflammation[J]. Frontiers In Medicine, 2023.10.

10.  Haiwang Wang, Duo Li, Yuansen Chen, Ziquan Liu, Yanqing Liu, Xiangyan Meng, Haojun Fan, Shike Hou. Shear-induced acquired von Willebrand syndrome: an accomplice of bleeding events in adults on extracorporeal membrane oxygenation support Front Cardiovasc Med. 2023,36:100767.

11.  Mingming Guo, Bowen Li, Guoqing Feng, Xin Su, Xue Wang, Xiaoxuan Han, Manyi Yang, Lipeng Bai, Xiaodong Zhu, HaojunFan, Bin Zheng. Engineered inhalable nanocatalytic therapeutics for Parkinson’s disease by inducing mitochondrial autophagy[J]. Materials & Design, 2023,228: 111808.

12.  Liu Tao, Liu Xin, Li Yue, Wang Aitian, Chen Shuohua, Wu houling, Hou Shike, Fan Haojun, Cao Chunxia. Associations of Traumatic Injury with Abnormal Glucose Metabolism: A Population-Based Prospective Cohort Study[J]. Clinical Epidemiology, 2023,15:325-336.

13.  Li Yue Li Ji, Geng Jiayu, Liu Tao, Liu Xin, Fan Haojun, Cao Chunxia. Urban-sub-urban-rural Vriation in The Supply and Demand of Emergency Medical Services[J]. Frontiers In Public Health, 2023,10.

14.  Lin Huishu, Liu Qisijing, Zhao Lei, Liu Ziquan, Cui Huanhuan, Li Penghui, Fan Haojun, Guo Liqiong. Circulating Pulmonary-Originated Epithelial Biomarkers for Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis[J]. International Journal Of Molecular Sciences, 2023,24(7).

15.  Cai Jinxia, Abudou Halidan, Chen Yuansen, Wang Haiwang, Wang Yiping, Li Wenli, Li Duo, Niu Yanxiang, Chen Xin, Liu Yanqing, Li Yongmao, Liu Ziquan, Meng Xiangyan, Fan Haojun. The Effects of ECMO on Neurological Function Recovery of Critical Patients: A Double-edged Sword[J]. Frontiers in Medicine, 2023,10:1117214.

16.  Chen Yuansen, Li Duo, Liu Ziquan, Liu Yanqing, Fan Haojun, Hou Shike. Research Progress of Portable Extracorporeal Membrane Oxygenation[J]. Expert Review Of Medical Devices. 2023,20(3):221-232.

17.  Sang Lu, Guo Xiaoqin, Fan Haojun, Shi Jie, Hou Shike, Lv Qi. Esenchymal Stem Cell-Derived Extracellular Vesicles as Idiopathic Pulmonary Fibrosis Microenvironment Targeted Delivery[J]. Cells, 2022, 11(15):2322.

18.  Jin Hongxia, Lu Lu, Fan Haojun. Global Trends and Research Hotspots in Long COVID: A Bibliometric Analysis[J]. International Journal of Environmental Research and Public Health, 2022,19(6):3742.

19.  Sang Lu, Guo Xiaoqin, Zhao Yuchen, Shi Jie, Niu Zhifang, Wu Zhenlong, Hou Shike, Fan Haojun, Lv Qi. Protective Effect of Nebulized Heparin in the Animal Models of Smoke Inhalation Injury: A Meta-analysis and Systematic Review of Experimental Studies[J]. J Burn Care Res, 2022, 21:irac156.

20.  Niu Zhifang Ding ZilingChan Yion Yan Li Zhang Wenyu Wang Hongyu Jie ShiQi Lv Shike Hou Xiaoqin Guo Haojun Fan. Clinical characteristics and predictors of burn complicated with smoke inhalation injury: A retrospective analysis[J]. Experimental and Therapeutic Medicine, 2022, 24(6:758.

21.  Lu Qianying, Yu Sifan, Meng Xiangyan, Shi Mingyu , Huang Siyu, Li Junfeng, Zhang Jianfeng, Liang Yangfan, Ji Mengjun, Zhao Yanmei, Fan Haojun. MicroRNAs: Important Regulatory Molecules in Acute Lung Injury/Acute Respiratory Distress Syndrome[J]. International Journal Of Molecular Sciences, 2022,23(10):5545.

22.  Meng Xiangyan, Lu Qianying, Zhang Jianfeng, Li Junfeng, Shi Mingyu, Huang Siyu, Yu Sifan, Zhao Yanmei, Fan Haojun. A Novel Animal Model of Primary Blast Lung Injury and Its Pathological Changes in Mice[J]. Journal of Trauma and Acute Care Surgery, 2022 93(4):530-537.

23.  Li Wenli, Li Duo, Chen Yuansen, Abudou Halidan, Wang Haiwang, Cai Jinxia, Wang Yiping, Liu Ziquan, Liu Yanqing, Fan Haojun. Classic Signaling Pathways in Alveolar Injury and Repair Involved in Sepsis-Induced ALI/ARDS: New Research Progress and Prospect[J]. Disease markers, 2022,6362344.

24.  Sang Lu, Guo Xiaoqin, Shi Jie, Hou Shike, Fan Haojun, Lv Qi, Morsczeck Christian. Characteristics and Developments in Mesenchymal Stem Cell Therapy for COVID-19: An Update[J]. Stem Cells International, 2021:5593584.

25.  Lu Qianying, Huang Siyu, Meng Xiangyan, Zhang Jianfeng, Yu Sifan, Li Junfeng, Shi Mingyu, Fan Haojun, Zhao Yanmei. Mechanism of Phosgene-Induced Acute Lung Injury and Treatment Strategy[J]. International Journal of Molecular Sciences, 2021,22(20).

26.  Cao Chunxia, Li Yue, Fu Shaobo, Zhang Yongzhong, Li Ning, Hou Shike, Fan Haojun. Patient delay in a coronavirus disease 2019 (COVID-19) outbreak in Tianjin. China from January to February 2020[J]. Journal of the Formosan Medical Association, 2021.PP1-9.

27.  Lv Qi, Long Manman, Wang Xin, Shi Jie, Wang Pengtao, Guo Xiaoqin, Song Jie, Midgley C. Adam, Fan Haojun, Hou Shike. The Role of Alpha-1-Acid Glycoprotein in the Diagnosis and Treatment of Crush Syndrome-Induced Acute Kidney Injury[J]. Shock, 2021,56(6):1028-1039.

28.  Li Yue, Hou Shike, Zhang Yongzhong, Liu Junfeng, Fan Haojun, Cao Chunxia. Effect of Travel Restrictions of Wuhan City Against COVID-19: A Modified SEIR Model Analysis[J]. Disaster medicine and public health preparedness, 2021. PP 1-7.

29.  Li N, Geng C, Hou S, Fan H and Gong Y: Damage-Associated Molecular Patterns and Their Signaling Pathways in Primary Blast Lung Injury: New Research Progress and Future Directions[J]. Int J Mol Sci, 2020, 21(17): 6303.

30.  Shen Shao, Zichen Zhou, Yue Li, Shuyu Liu, Lu Lu, Shike Hou, Bin Fan, Chunxia Cao, Haojun Fan. Experiences and Practices in the Current Prevention 3 and Control of the Novel Coronavirus Pneumonia 4 in China[J]. Disaster Medicine and Public Health Preparedness, 2020,9(173):1-10.

31.  Yanqing Liu, Hui Wang, Ziquan Liu, Yanjun Gu , Limin Xin, Jinyang Liu and Haojun Fan. Short term exposure to high intensity sound induces hearing loss and apoptosis in guinea pigs[J]. Acta Neurobiol Exp, 2019, 79(2): 155-168.

32.  Lv Q, Ding H, Liu ZQ, Gao HW, Yu BG, Wu ZW, Fan HJ, Hou SK. The Role of CD46 Polymorphisms in the Occurrence of Disease in Chinese Young Men with Human Adenovirus Type 55 Infection[J]. Disaster Med Public Health Prep, 2018,12(4):427-430.

33.  Hou SK, Lv Q, Ding H, Zhang YZ, Yu BG, Liu ZQ, Su B, Liu JY, Yu MY, Sun ZG, Fan HJ. Disaster medicine in China: present and future[J]. Disaster Med Public Health Prep, 2018,12(2):157-165.

34.  Xiao P, Sun S, Cao J, Wang J, Li H, Hou S, Ding H, Liu Z, Fang Y, Bai S, Qin X, Yu F, Liu J, Wang X, Lv Q, Fan H. Expression profile of microRNAs in bronchoalveolar lavage fluid of rats as predictors for smoke inhalation injury[J]. Burns, 2018,44(8):2042-2050.

35.  纪孟君,赵艳梅,路倩颖,孟祥艳,樊毫军.体外膜肺氧合在严重创伤患者救治中的并发症及其防治策略研究进展[J].中华创伤杂志,2023,39(02):178-184.

36.  刘姝昱,刘鑫,刘涛,樊毫军,曹春霞.城市震后应急食品供应优化调配模型研究[J].自然灾害学报,2022,31(2):73-79.

37.  樊毫军,靳红霞,卢鲁. 基于文献计量分析的国际视角下灾难医学热点问题研究[J].灾害学2022,37(03):1-13.

38.  孟祥艳,赵艳梅,路倩颖,张健峰,黄思宇,樊毫军.肺康复在急性呼吸窘迫综合征治疗中的应用进展[J].中国康复医学杂志,2022,37(6):845-849.

39.  张健峰,黄思宇,孟祥艳,路倩颖,樊毫军,赵艳梅.原发性肺爆震伤的相关研究进展[J].中华急诊医学杂志,2021,30(03):370-374.

40.  樊毫军,李文莉,哈力旦•阿布都,蔡金霞,陈原森,刘燕青,刘子泉.体外膜肺氧合在院外急救救援现场和转运后送中的应用[J].中华灾害救援医学,2021,9(08):1157-1161.

41.  李文莉,刘燕青,蔡金霞,陈原森,王海旺,史源,刘子泉,樊毫军.体外膜肺氧合支持下的急性呼吸窘迫综合征动物模型研究进展[J].中华灾害救援医学,2021,9(08):1176-1179.

42.  刘子泉,崔欢欢,刘燕青,郭丽琼,孟祥艳,赵艳梅,柴慈婧,毕珣,樊毫军.高原肺水肿的诊断、治疗与预防[J].中华灾害救援医学,2021,9(08):1162-1166.

43.  陈原森,刘子泉,王海旺,蔡金霞,李文莉,侯世科,樊毫军,张伟丽,刘燕青.大鼠体外膜肺氧合设备的研制与模型应用[J].中华灾害救援医,2021,9(08):1171-1175.

 

【专利软著】

1、樊毫军,刘燕青,陈原森,李传龙,李勇男,刘子泉,孟祥艳,李咏懋,石悦,李文莉,李铎,姚梓轩. 一种用于动物的ECMO实验装置及其方法,ZL202310486192.0

2、郑斌、樊毫军、李博文、华婷婷. 一种高抗凝ECMO和体外循环耗材,ZL202211016979.2

3、郑斌,樊毫军,李博文,华婷婷. 一种高抗凝体外循环管路,ZL202211017068.1

4、苏楠,樊毫军,和建伟. 一种铅锤式自动水平机构,ZL202210932257.5

5、李桂丹,贺桐,樊毫军,高鹏,刘子泉,李斌. 五相电机开路故障容错运行时母线电容器电流分析方法,ZL202211210784.1

6、刘子泉、丁辉、赵艳梅、刘越、田学忠、刘燕青、郭丽琼、樊毫军、侯世科、崔欢欢、李文莉、蔡金霞、陈原森、董文龙. 一种截肢工具存放箱,ZL202110509554.4

7、刘子泉,樊毫军,刘燕青,郭丽琼,侯世科,孟祥艳,董文龙,崔欢欢,陈原森,李文莉,蔡金霞. 球形动物高压舱,ZL202130082513.2

8、侯世科,樊毫军,白松,张永忠,吕琪,曹春霞,刘子泉,赵艳梅,孟祥艳,卢鲁,董文龙,卢明,史杰. 春秋季医疗救援服,ZL202021067312.1

9、侯世科,樊毫军,白松,张永忠,吕琪,曹春霞,刘子泉,赵艳梅,孟祥艳,卢鲁,董文龙,卢明,史杰. 夏季医疗救援服,ZL202021067335.2

10、侯世科,樊毫军,白松,张永忠,吕琪,曹春霞,刘子泉,赵艳梅,孟祥艳,卢鲁,董文龙,卢明,史杰. 医疗救援充气帐篷,ZL202021067977.2

11、侯世科,樊毫军,白松,张永忠,吕琪,曹春霞,刘子泉,赵艳梅,孟祥艳,卢鲁,董文龙,卢明,史杰. 医疗救援马甲,ZL202021067978.7

12、樊毫军,范斌,侯世科,董文龙,赵艳梅,王超、壬方、何萌. 火灾爆炸医学救援模拟演练培训系统,2020SR0764310

13、范斌,樊毫军,侯世科,董文龙,卢明,韦薇,王超,何萌. 地震医学救援模拟演练培训系统,2020SR0764317

14、侯世科,樊毫军,范斌,卢明,董文龙,孙振兴. 一种医疗设备装载车,ZL201210054533.9

15、侯世科,樊毫军,卢明,范斌,孙振兴,董文龙. 一种医务人员输送宿营车. ZL201210054531.x

16、侯世科,樊毫军,武周炜,于宝国,温剑,丁辉,卢明,孙振兴. 一种方舱医疗系统,ZL201210457696.1

17、侯世科,樊毫军,武周炜,于宝国,温剑,丁辉,卢明,孙振兴. 一种方舱医疗系统用CT方舱. ZL201210455512.8

18、侯世科,樊毫军,武周炜,于宝国,温剑,丁辉,卢明,孙振兴. 一种用于方舱医疗系统的CT方舱. ZL201210455514.7

19、侯世科,樊毫军. 野战便携式血液净化机. ZL 201610428083.3

20、侯世科,樊毫军. 模拟动物烟雾吸入伤发生器,ZL201610428082.7

21、侯世科,樊毫军. 动物挤压伤模拟平台,ZL 201610428085.2

 

【参编教材】

  曹春霞、樊毫军主编,灾难流行病学理论与实践,人民卫生出版社,2023.10ISBN978-7-117-35214-7

  樊毫军、曹春霞主编,职业安全与健康防护科普丛书——电力行业人员篇,人民卫生出版社,2022.09ISBN978-7-117-33527-0

  侯世科、樊毫军、郑静晨主编,救援防护医学,华中科技大学出版社,2022.09ISBN978-7-568-08719-3

  侯世科、樊毫军主编,全民防灾自救知识读本—中国灾难医学初级教程,华中科技大学出版社,2020.04ISBN978-7-5680-6036-3

  侯世科、樊毫军主编,中国灾难医学高级教程,华中科技大学出版社,2019.09ISBN978-7-5680-5499-7

  侯世科、樊毫军主译,Ciottone灾难医学(第2版),人民卫生出版社,2018.10ISBN978-7-117-25343-7

  侯世科、樊毫军、张永忠主编,灾害医学救援系统工程,科学出版社,2018.02ISBN978-7-03-053303-6

  侯世科、樊毫军主编,整合救援医学,人民卫生出版社,2018.01ISBN978-7-117-24996-6

  侯世科、樊毫军主编,灾难医学.装备篇,人民卫生出版社,2017.06ISBN978-7-117-23857-1

  侯世科、樊毫军主编,灾难医学.技术篇,人民卫生出版社,2017.06ISBN 978-7-117-23856-4

  侯世科、樊毫军主编,灾难医学.管理篇,人民卫生出版社,2017.06ISBN978-7-117-23854-0

  侯世科、陈锋、樊毫军主译,高原病,军事医学出版社,2016.12ISBN978-7-5163-0693-2

  郑静晨、侯世科、樊毫军主编,国内外重大灾害救援案例剖析,科学出版社,2011.05ISBN978-7-0303-0894-8

  郑静晨、侯世科、樊毫军主编,灾害救援医学,科学出版社,2008.05ISBN9787030202765

 

【科技获奖】

l  樊毫军(2/9), 我国重大突发事件应急医学救援模块化体系创建及应用, 国家科技进步二等奖, 2014.12

l  樊毫军(3/9), 重大自然灾害医疗救援体系的创建及关键技术、装备研发及应用,国家科技进步二等奖, 2009.12

l  樊毫军(2/12), 急进高原救援群体性高原反应机制及防治研究,天津市人民政府, 科技进步, 省部一等奖, 2017.2

l  樊毫军(2/12), 强震巨灾后人员伤亡预测与救援智能决策系统的研究, 天津市人民政府, 科技进步, 省部一等奖, 2013.2

l  樊毫军(2/9), 高原高寒地震救援关键技术与装备研发, 中国人民武装警察部队科学委员会, 科技进步, 省部一等奖, 2014.3