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胡亦辰

职称/职务:英才副教授
办公室:医工院办公楼213
邮箱:yhu@tju.edu.cn

个人简介:

 

胡亦辰博士长期从事磁共振技术的研究,于2017年毕业于美国伊利诺伊大学,获磁共振专业博士学位,后入职United Imaging Healthcare, America (联影医疗美国)磁共振研究中心任Senior Scientist,后任Lead Scientist,任职期间主持了多项磁共振高级应用的技术开发和研究,成功应用于三甲医院的临床诊断和高校及科研院所的研究之中,并产生了多篇学术论文及十余项专利。在神经影像序列方面,主持了3D ASL,多PLD ASL等技术研发,以非侵入式的标记获得脑血流灌注的定量信息,助力脑神经科研;实现了拥有业界自主知识产权的多对比度成像技术-Multiplex的基础序列,已体现出突出的科研价值。此外,主持了多种快速成像采集序列的研发,包括3D GRASE3D FSE Spiral等用以作为磁共振高级应用的采集方法,并在3D GRE Spiral3D bSSFP Spiral序列的研发过程中形成了SPARTA-3D序列簇集,可用于全身各部位的高时空分辨率的动态3D实时磁共振采集,对于手术介入以及放射治疗的3D磁共振导航场景具有实用的临床应用价值,此外SPARTA-3D在多种心脏磁共振序列扫描中也具有临床推广前景。

 


主要研究方向:

 

  磁共振动脉自旋标记技术(ASL),脑血流灌注动力学

  磁共振快速成像序列

  实时磁共振成像方法

  磁共振成像方法在手术介入与治疗的临床应用

 

代表性学术成果:

论文:

 

               Li, H., Liu, Q., Dong, X., Guo, Z., Wang, K., Liu, S., Liu, Q.,   Ye, Y., Hu, Y., Zhong, Z., Liu, H., Zhu, Y., Wang, H., Liang, D., Xu,   J., and Zhou, Y., “Robust cardiac T1 mapping in three heartbeats with   UltraMAP: a synergistic CNN-FC approach”. IEEE International Symposium on   Biomedical Imaging (ISBI).

May 2024

 

               Hu, Y., Zhong, Z., Liu, Q., Li,   H., Liu, H., Ye, Y., and Xu, J., “Feasibility of real-time 3D whole heart MR   cine based on bssfp sequence using spiral in-out trajectory”. Journal of   Cardiovascular Magnetic Resonance. (IF=4.2)

Mar 2024

 

               Hu, J., Guo, M., Hu, Y., Liu, Q., Ye, Y., and Xu, J., “A   dual interleaved k-space trajectory for robust bssfp imaging of high-quality   cardiac cine MRI”. Journal of Cardiovascular Magnetic Resonance. (IF=4.2)

Mar 2024

 

               Hu, Y., Wei, Q., Zhou, Z., Hu,   J., Xie, J. and Xu, J., “Customized whole brain-covering 3D GRASE in   multi-delay pseudo-continuous arterial spin labeling for duplex distinct   hemodynamic mapping contrasts of brain tissues and circulation pathways”. Physics   in Medicine and Biology. (IF=4.174)

Aug 2022

 

               Ye, Y., Lyu, J., Hu, Y., Zhang, Z., Xu, J., Zhang, W.,   Yuan, J., Zhou, C., Fan, W., and Zhang, X., “Augmented   T1-weighted steady state magnetic resonance imaging”.   NMR in Biomedicine. (IF=4.044)

Mar 2022

 

               Ye, Y., Lyu, J., Hu, Y., Zhang, Z., Xu, J., and Zhang,   W., “MULTI-parametric MR imaging with fLEXible design (MULTIPLEX)”. Magnetic   Resonance in Medicine. (IF=4.668)

Aug 2021

 

               Chen, E.Z., Ye, Y., Chen, X., Lyu, J., Zhang, Z., Hu, Y.,   Chen, T., Xu, J., and Sun, S., “Accelerating 3D MULTIPLEX MRI Reconstruction   with Deep Learning”.  Cornell University, arXiv.org > eess   > arXiv:2105.08163.

May 2021

 

               Nacken, T.J., Halbig, C.E., Wawra, S.E., Damm, C., Romeis, S.,   Walter, J., Tehrani, M.J., Hu, Y., Ishii, Y., Eigler, S., and Peukert,   W., “Structural factors controlling size reduction of graphene oxide in   liquid processing”. Carbon. (IF=9.594)

Dec 2017

 

               Hu, Y., Shim, Y., Oh, J., Park,   Sunghee, Park, Sungjin, and Ishii, Y., “Synthesis of 13C, 15N-labeled   graphitic carbon nitrides and NMR-based evidence of hydrogen-bonding assisted   two-dimensional assembly”. Chemistry of Materials. (IF= 9.811)

May 2017

 

               Wang, Z., Eigler, S., Ishii, Y., Hu, Y., Papp, C.,   Lytken, O., Steinrück, H.P., and Halik, M., “A facile approach to synthesize   an oxo-functionalized graphene/polymer composite for low-voltage operating   memory devices”. Journal of Materials Chemistry C, 3(33),   pp.8595-8604. (IF=7.393)

Jul 2015

 

               Eigler, S., Hu, Y., Ishii, Y., and Hirsch, A.,   “Controlled functionalization of graphene oxide with sodium azide”. Nanoscale, 5(24),   pp.12136-12139. (IF= 7.790)

Oct 2013

 

               Park, S., Hu, Y., Hwang, J.O., Lee, E.S., Casabianca,   L.B., Cai, W., Potts, J.R., Ha, H.W., Chen, S., Oh, J., Kim, S.O., Kim, Y.H.,   Ishii, Y. and Ruoff, R.S., “Chemical   structures of hydrazine-treated graphene oxide and generation of aromatic   nitrogen doping”. Nature Communications, 3, p.638. (IF= 14.919)

Jan 2012

会议:

          Hu, Y., Hu, J., Zhong, Z.,   Padua, A., Liu, Q., Ye, Y., and Xu, J., “SPARTA-3D: 3D real-time tracking   solution for interventional MRI”, International Society for Magnetic   Resonance in Medicine Annual Meeting & Exhibition, 2024. Oral Power Pitch.

May 2024

 

          Hu, Y., Zhong, Z., Hu, J., Li,   H., Liu, H., Liu, Q., Ye, Y., and Xu, J., “3D   real-time whole heart cine MR based on spiral-in/out bssfp sequence”, International Society for   Magnetic Resonance in Medicine Annual Meeting & Exhibition, 2024. Digital Poster.

May 2024

 

          Hu, Y., Hu, J., Zhang, Z., Liu,   H., Liu, Q., Ye, Y., and Xu, J., “Subject-specific circular artifacts in ASL perfusion imaging   with 3D stack-of-spirals FSE readout”, International   Society for Magnetic Resonance in Medicine Annual Meeting & Exhibition, 2023. Digital Poster.

Jun 2023

 

          Hu, Y., Wei, Q., Zhou, Z., Hu, J., Xie, J. and Xu, J., “Customized   whole-brain covering GRASE in multi-delay pCASL for distinct contrasts and   adequate SNRs in hemodynamic parameter mappings”, International Society   for Magnetic Resonance in Medicine 30th Annual Meeting & Exhibition, 2022   . Oral Power Pitch.

Dec 2021

 

          Hu, Y., and Hu, J., “Simplified   Phase-Sensitive Inversion Recovery (PSIR) Reconstruction using   Multi-dimensional Integration (MDI) for Elevated SNR”, International   Society for Magnetic Resonance in Medicine 29th Annual Meeting & Exhibition,   2021. Digital Poster.

Feb   2021

 

          Chen, E.Z., Ye, Y., Chen, X., Lyu, J., Zhang, Z., Hu, Y.,   Chen, T., Xu, J., and Sun, S., “Accelerating 3D MULTIPLEX MRI Reconstruction   with Deep Learning”, International Society for Magnetic Resonance in   Medicine 29th Annual Meeting & Exhibition, 2021. Digital Poster.

Feb   2021

 

          Ye, Y., Lyu, J., Hu, Y., Zhang, Z., Xu, J., and Zhang,   W., “MULTI-Parametric MR imaging with fLEXible modular design (MULTIPLEX)”,   International Society for Magnetic Resonance in Medicine 29th Annual Meeting & Exhibition,   2021. Oral Talk.

Feb   2021

 

          Ye, Y., Lyu, J., Hu, Y., Zhang, Z., Xu, J., and Zhang,   W., “Augmented T1 weighted (aT1W) contrast imaging”, International Society   for Magnetic Resonance in Medicine 29th Annual Meeting & Exhibition,   2021. Digital Poster.

Feb   2021

 

          Hu, Y., Wei, Q., Zhou, Z., Xie,   J. and Ye, Y., “Noise reduction and ghosting alleviation in ASL perfusion   measurement using multi-dimensional integration (MDI)”, International   Society for Magnetic Resonance in Medicine 28th Annual Meeting & Exhibition,   2020. Digital Poster.

Feb   2020

 

          Li, G., Liu, H., Liu, Q., Ye, Y., Hu, Y., Qin, H., Xie,   J., Yan, J., Xin, Y. and Jiang, G., “A comparative analysis of CEST-APT,   SWI-QSM, DWI and ASL-CBF in ischemic stroke patients”, International   Society for Magnetic Resonance in Medicine 28th Annual Meeting & Exhibition,   2020. Oral Talk.

Feb   2020

 

          Ye, Y., Lv, J., Hu, Y., Zhang, Z., Xu, J. and Zhang W.,   “Complex semi-quantitative noise analysis for single set of MR images”,   International Society for Magnetic Resonance in Medicine 28th Annual Meeting & Exhibition,   2020. Digital Poster.

Feb   2020

 

          Hu, Y., Eigler, S., Ruoff. R.S.   and Ishii, Y., “Characterizations of chemically modified graphite/graphene   oxide by NMR and ab-initio calculations”, International Society of   Magnetic Resonance (ISMAR) 2015. Poster Presentation.

Aug   2015

 

          Hu, Y., Eigler, S., Ruoff. R.S.   and Ishii, Y., “Solid-state NMR investigation of chemically modified   graphite/graphene-based materials”, Chicago Area NMR Meeting for   Midwest-2014. Northwestern University, Evanston, IL. Invited   Talk.

Nov   2014

 

          Hu, Y., Wang, S., Zhu, Y.,   Ruoff, R.S. and Ishii, Y., “Structural analysis of activated   microwave-expanded graphite oxide and its confining behavior for small   molecules by solid-state NMR and solution NMR”, 54th Experimental   NMR Conference-2013. Poster Presentation.

Apr   2013

 

          Wang, S., Hu, Y., Park, S., Ruoff, R.S. and Ishii, Y.,   “Characterization of chemical reactions and structures for hydrazine-treated   graphene oxide and porous graphene-based materials by solid-state NMR and ab-initio   calculations”, 54th Rocky Mountain Conference on Magnetic   Resonance-2012. Poster Presentation.

Jul   2012

 

          Hu, Y., Park, S., Ruoff, R.S.   and Ishii, Y., “Characterization of reduced graphite oxide by 13C   and 15N solid-state NMR and ab-initio calculations”, 52nd   Experimental NMR Conference-2011. Poster Presentation.

Apr   2011

 






著作章节:

          《磁共振成像技术与应用》   上海科学技术出版社

2022

专利:

          Hu, Y., and Xu, J., “A 3D MR imaging method, system, and media”. Chinese   Patent.

2024

          Hu, Y., and Hu, J., “A density-compensation determination method,   system, and media”. Chinese Patent.

2023

          Hu, Y., and Hu, J., “An image reconstruction method, system, and   media”. Chinese Patent.

2023

          Hu, Y., and Hu, J., “An   echo-time shifting method in echo-planar imaging in MRI”. Chinese Patent.

2021

          Hu, Y., and Hu, J., “A   perfusion and CBF quantification method in arterial spin labeling MRI”. Chinese   Patent.

2021

          Hu, J., and Hu, Y., “An anatomical image acquisition   method in MRI”. Chinese Patent.

2021

          Hu, J., and Hu, Y., “An automatic positioning method in   MRI”. Chinese Patent.

2021

 

          Hu, J., and Hu, Y., “A self-navigated   dynamic cardiovascular imaging method in MRI”. Chinese   Patent.

2021

          Hu, J., and Hu, Y., “A quantification imaging interface   in MRI”. Chinese Patent.

2021

          Hu, Y., and Hu, J., “A variable   contrast spiral imaging acquisition method in MRI”. Chinese Patent.   202110720949.9

2020

          Hu, Y., and Hu, J., “A k-space   data sampling and regridding method in MRI”. Chinese Patent. 202110721080.X

2020

          Wei, Q., Xie, J., and Hu, Y., “Artifact elimination   method of ASL imaging based on GRASE readout”. Chinese Patent.   202010285038.3

2020

          Liu, H., Liu, Q., and Hu, Y., “Simultaneous acquisition   of APT, pH weighted image, R2, R2*, R2’ images and myelin water fraction map   by using 2D/3D GRASE sequence”. Chinese Patent. 202111106476.X

2019

          Liu, H., Liu, Q., and Hu, Y., “Systems   and methods for magnetic resonance imaging”.   US Patent. US17/033,001

2019